Zic Family Member 4 (ZIC4) (C-Term), (AA 299-334) antibody

Details for Product No. ABIN389183
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Antigen
Synonyms XlZic4
Epitope
C-Term, AA 299-334
(11), (10), (10), (9), (6), (3), (1), (1), (1)
Reactivity
Human
(53), (4), (2), (1), (1)
Host
Rabbit
(27), (25), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(3), (3), (3), (3), (3), (3)
Application
Western Blotting (WB)
(52), (37), (14), (6), (6)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN389183
291.50 $
Plus shipping costs $45.00

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Immunogen This ZIC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 299-334 AA from the C-terminal region of human ZIC4.
Clone RB10545
Isotype Ig
Specificity This ZIC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305~334 amino acids from the C-term region of human ZIC4.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ZIC4
Background ZIC4 is a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5.
Synonyms: Zinc finger protein ZIC 4, Zinc finger protein of the cerebellum 4, ZIC4
Molecular Weight 36567 DA
Gene ID 84107
UniProt Q8N9L1
Research Area Stem Cells
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.45 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Zic Family Member 4 (ZIC4) (C-Term), (AA 299-334) antibody Western blot analysis of ZIC4 (arrow) using rabbit polyclonal ZIC4 Antibody (C-term) (ABIN389183). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ZIC4 gene (Lane 2) (Origene Technologies).
Background publications Grinberg, Northrup, Ardinger et al.: "Heterozygous deletion of the linked genes ZIC1 and ZIC4 is involved in Dandy-Walker malformation." in: Nature genetics, Vol. 36, Issue 10, pp. 1053-5, 2004 (PubMed).

Ishiguro, Inoue, Mikoshiba et al.: "Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family." in: Biochemical and biophysical research communications, Vol. 324, Issue 1, pp. 302-7, 2004 (PubMed).

Validation Images
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