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Details for Product No. ABIN389244

Collagen, Type IX, alpha 1 (COL9A1) (AA 428-456), (Center) antibody

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Antigen
Synonyms DJ149L1.1.2, EDM6, MED, STL4, Col9a-1, cb339, sb:cb339, zgc:85892, wu:fa12a12, wu:fa12d02, wu:fc22c08, wu:fc38d08, edm6, MGC82441
Epitope
»Alternatives AA 428-456, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN389244
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This COL9A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-456 AA from the Central region of human COL9A1.
Clone RB13831
Isotype Ig
Specificity This COL9A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 435~464 amino acids from the Center region of human COL9A1.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name COL9A1
Background COL9A1 is one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule,and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects.
Synonyms: Collagen alpha-1(IX) chain [Precursor], COL9A1
Molecular Weight 91855 DA
Gene ID 1297
UniProt P20849
Research Area Stem Cells, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Liu, Jin, Cao et al.: "[Analysis of association between COL9A1 gene and idiopathic congenital talipes equinovarus]." in: Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji, Vol. 29, Issue 4, pp. 427-32, 2007 (PubMed).

Fresquet, Jowitt, Ylöstalo et al.: "Structural and functional characterization of recombinant matrilin-3 A-domain and implications for human genetic bone diseases." in: The Journal of biological chemistry, Vol. 282, Issue 48, pp. 34634-43, 2007 (PubMed).

Alternatives for antigen "Collagen, Type IX, alpha 1 (COL9A1)", type "Antibodies"
Hosts (4), (2)
Reactivities (6)
Applications (5), (2), (1), (1)
Epitopes (2), (1), (1), (1)
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