You are viewing an incomplete version of our website. Please click to reload the website as full version.

Collagen, Type IX, alpha 1 (COL9A1) (AA 428-456), (Center) antibody

Details for Product No. ABIN389244, Supplier: Log in to see
Antigen
  • cb339
  • sb:cb339
  • zgc:85892
  • wu:fa12a12
  • wu:fa12d02
  • wu:fc22c08
  • wu:fc38d08
  • edm6
  • MGC82441
  • DJ149L1.1.2
  • EDM6
  • MED
  • STL4
  • Col9a-1
Epitope
AA 428-456, Center
16
9
6
3
2
1
1
1
Reactivity
Human
36
3
2
Host
Rabbit
30
7
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
30
23
18
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Available images

Immunogen This COL9A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-456 AA from the Central region of human COL9A1.
Clone RB13831
Isotype Ig
Specificity This COL9A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 435~464 amino acids from the Center region of human COL9A1.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name COL9A1 (COL9A1 Antibody Abstract)
Background COL9A1 is one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule,and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in the COL9A1 gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects.
Synonyms: Collagen alpha-1(IX) chain [Precursor], COL9A1
Molecular Weight 91855 DA
Gene ID 1297
UniProt P20849
Research Area Stem Cells, Cell Structure
Pathways
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Collagen, Type IX, alpha 1 (COL9A1) (AA 428-456), (Center) antibody (ABIN389244) Western blot analysis of anti-COL9A1 Antibody (Center) (ABIN389244) in 293 cell line ...
Immunohistochemistry (IHC) image for anti-Collagen, Type IX, alpha 1 (COL9A1) (AA 428-456), (Center) antibody (ABIN389244) Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with COL9A...
Background publications Fresquet, Jowitt, Ylöstalo et al.: "Structural and functional characterization of recombinant matrilin-3 A-domain and implications for human genetic bone diseases." in: The Journal of biological chemistry, Vol. 282, Issue 48, pp. 34634-43, 2007 (PubMed).

Liu, Jin, Cao et al.: "[Analysis of association between COL9A1 gene and idiopathic congenital talipes equinovarus]." in: Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji, Vol. 29, Issue 4, pp. 427-32, 2007 (PubMed).