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Details for Product No. ABIN389412

Elongator Acetyltransferase Complex Subunit 2 (ELP2) (C-Term), (AA 737-765) antibody

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Synonyms Epl2, StIP1, Statip1, AU023723, SHINC-2, STATIP1, StIP, F14J22.24, elongator protein 2
»Alternatives C-Term, AA 737-765
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Immunofluorescence (IF), Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN389412
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This ELP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 737-765 AA from the C-terminal region of human ELP2.
Clone RB18010
Isotype Ig
Specificity This ELP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744~773 amino acids from the C-terminal region of human ELP2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name ELP2
Background ELP2 regulates the ligand-dependent activation of STAT3. The protein acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.
Synonyms: Elongator complex protein 2, ELP2, STAT3-interacting protein, StIP1, SHINC-2, STATIP1, ELP2
Molecular Weight 92500 Da (isoform 2 (84kd) was detected by WB test) Da
Gene ID 55250
UniProt Q6IA86
Research Area Stem Cells
Application Notes Recommend dilutions: IF : 1:100,WB : 1:1000,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Hawkes, Otero, Winkler et al.: "Purification and characterization of the human elongator complex." in: The Journal of biological chemistry, Vol. 277, Issue 4, pp. 3047-52, 2002 (PubMed).

Kim, Lane, Reinberg: "Human Elongator facilitates RNA polymerase II transcription through chromatin." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 3, pp. 1241-6, 2002 (PubMed).

Alternatives for antigen "Elongator Acetyltransferase Complex Subunit 2 (ELP2)", type "Antibodies"
Hosts (14)
Reactivities (12), (2)
Applications (13), (7), (2), (2), (1), (1)
Epitopes (5), (1), (1), (1), (1)