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ABL1 antibody (pTyr204)

ABL1 Reactivity: Human IF, DB Host: Rabbit Polyclonal RB7973 unconjugated
Catalog No. ABIN389865
  • Target See all ABL1 Antibodies
    ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
    Binding Specificity
    • 36
    • 33
    • 21
    • 20
    • 16
    • 15
    • 15
    • 15
    • 15
    • 15
    • 15
    • 15
    • 15
    • 12
    • 12
    • 9
    • 9
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr204
    Reactivity
    • 255
    • 142
    • 107
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 339
    • 2
    Rabbit
    Clonality
    • 339
    • 2
    Polyclonal
    Conjugate
    • 111
    • 25
    • 23
    • 21
    • 14
    • 14
    • 14
    • 14
    • 14
    • 14
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    This ABL1 antibody is un-conjugated
    Application
    • 224
    • 143
    • 143
    • 142
    • 77
    • 58
    • 33
    • 32
    • 27
    • 17
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Dot Blot (DB)
    Predicted Reactivity
    Zf, M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ABL Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y185 of human ABL.
    Clone
    RB7973
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ABL1 Primary Antibody
  • Application Notes
    IF: 1:10~50. DB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
    Alternative Name
    ABL (ABL1 Products)
    Synonyms
    ABL antibody, JTK7 antibody, bcr/abl antibody, c-ABL antibody, p150 antibody, v-abl antibody, AI325092 antibody, Abl antibody, E430008G22Rik antibody, c-Abl antibody, ABL proto-oncogene 1, non-receptor tyrosine kinase antibody, c-abl oncogene 1, non-receptor tyrosine kinase antibody, Tyrosine-protein kinase abl-1 antibody, ABL1 antibody, Abl1 antibody, abl-1 antibody, abl1 antibody
    Background
    ABL1 is a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9,22) translocation results in the head-to-tail fusion of the BCR and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1.
    Molecular Weight
    122873
    Gene ID
    25
    NCBI Accession
    NP_005148, NP_009297
    UniProt
    P00519
    Pathways
    Apoptosis, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
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