BUD31 Homolog (Yeast) (BUD31) (N-Term), (AA 21-50) antibody

Details for Product No. ABIN390083
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Antigen
Synonyms G10, EDG2, EDG-2, C77604, Cwc14, YCR063W, fSAP17, Edg2
Epitope
N-Term, AA 21-50
(5), (1), (1), (1)
Reactivity
Human
(12), (8), (1)
Host
Rabbit
(12), (1)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB)
(11), (8), (7), (7), (3), (3), (1)
Pubmed 3 references available
Quantity 400 µL
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Catalog No. ABIN390083
291.50 $
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Immunogen This EDG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-50 AA from the N-terminal region of human EDG2.
Clone RB01825
Isotype Ig
Specificity This EDG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28~58 amino acids from the N-terminal region of human EDG2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name EDG2
Background The EDG2 integral membrane protein is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion.
Molecular Weight 41109 DA
Gene ID 1902
NCBI Accession NP_001392
Research Area Cell Signaling, Cell Structure, Cancer, Cell Cycle, Neurology
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-BUD31 Homolog (Yeast) (BUD31) (N-Term), (AA 21-50) antibody The anti-EDG2 N-term Antibody (ABIN390083) is used in Western blot to detect EDG2 in A375 lysate.
Background publications Van Leeuwen, Olivo, Grivell et al.: "Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1." in: The Journal of biological chemistry, Vol. 278, Issue 1, pp. 400-6, 2002 (PubMed).

Shida, Kitayama, Yamaguchi et al.: "Lysophosphatidic acid (LPA) enhances the metastatic potential of human colon carcinoma DLD1 cells through LPA1." in: Cancer research, Vol. 63, Issue 7, pp. 1706-11, 2003 (PubMed).

Matsuda, Suzuki, Honda et al.: "Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways." in: Oncogene, Vol. 22, Issue 21, pp. 3307-18, 2003 (PubMed).

Validation Images
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