Sphingosine-1-Phosphate Receptor 3 (S1PR3) (N-Term), (AA 1-30) antibody

Details for Product No. ABIN390084
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Antigen
Epitope
N-Term, AA 1-30
(22), (11), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(90), (24), (24), (11)
Host
Rabbit
(77), (14)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(66), (34), (20), (16), (9), (5), (4), (3), (2), (1), (1)
Pubmed 3 references available
Quantity 400 μL
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Catalog No. ABIN390084
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Immunogen This EDG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human EDG3.
Clone RB2224
Isotype Ig
Specificity This EDG3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6~36 amino acids from the N-terminal region of human EDG3.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name EDG3
Background EDG3 is a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.
Molecular Weight 42250 DA
Gene ID 1903
UniProt Q99500
Research Area Cell Cycle, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Sphingosine-1-Phosphate Receptor 3 (S1PR3) (N-Term), (AA 1-30) antibody The anti-EDG3 N-term Antibody (ABIN390084) is used in Western blot to detect EDG3 in mouse kidney lysate.
Background publications Ancellin, Hla: "Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5." in: The Journal of biological chemistry, Vol. 274, Issue 27, pp. 18997-9002, 1999 (PubMed).

Lee, Thangada, Claffey et al.: "Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate." in: Cell, Vol. 99, Issue 3, pp. 301-12, 1999 (PubMed).

Licht, Tsirulnikov, Reuveni et al.: "Induction of pro-angiogenic signaling by a synthetic peptide derived from the second intracellular loop of S1P3 (EDG3)." in: Blood, Vol. 102, Issue 6, pp. 2099-107, 2003 (PubMed).

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