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anti-Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6) (C-Term), (AA 508-538) ...

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Details for Product No. ABIN390248

Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6) (C-Term), (AA 508-538) antibody

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Catalog no.	ABIN390248
Quantity	400 µL
Price	291.50 $ Plus shipping costs $45.00

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Product details

Alternative Name	Parp6
Background	Poly(ADP-ribosyl)ation is an immediate DNA-damage-dependent post-translational modification of histones and other nuclear proteins that contributes to the survival of injured proliferating cells. Poly(ADP-ribose) polymerases (PARPs) now constitute a large family of 18 proteins, encoded by different genes and displaying a conserved catalytic domain in which PARP-1 (113 kDa), the founding member, and PARP-2 (62 kDa) are so far the sole enzymes whose catalytic activity has been shown to be immediately stimulated by DNA strand breaks. A large repertoire of sequences encoding novel PARPs now extends considerably the field of poly(ADP-ribosyl)ation reactions to various aspects of the cell biology including cell proliferation and cell death. Some of these new members interact with each other, share common partners and common subcellular localizations suggesting possible fine tuning in the regulation of this post-translational modification of proteins. Synonyms: Poly [ADP-ribose] polymerase 6, PARP-6, PARP6
Molecular Weight	71115 DA
Gene ID	56965
UniProt	Q2NL67
Research Area	Translation Factors, Cell Cycle, Signaling, Cell Structure

Alternatives for antigen "Poly (ADP-Ribose) Polymerase Family, Member 6 (PARP6)", type "Antibodies"

Immunogen	This Parp6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 508-538 AA from the C-terminal region of human Parp6.
Clone	RB14170
Isotype	Ig
Specificity	This Parp6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496~525 amino acids from the C-terminal region of human PARP6.
Predicted Reactivity	Mouse (Murine)
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Application Notes	Recommend dilutions: WB : 1:1000
Restrictions	For Research Use only

Format	Liquid
Concentration	2 mg/mL
Buffer	PBS with 0.09 % (W/V) sodium azide
Preservative	Sodium azide
Storage	4 °C/-20 °C
Storage Comment	Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date	6 months

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Antigen
Synonyms	ARTD17, PARP-6-B1, PARP-6-C, pART17, 1700119G14Rik, 2310028P13Rik, 3110038K10Rik, C030013N01Rik, PARP-6, RGD1310937
Epitope	Alternatives C-Term, AA 508-538 (11), (4), (2), (2), (1)
Reactivity	Alternatives Human (21), (4), (4), (2), (1), (1)
Host	Alternatives Rabbit (23)
Clonality (Clone)	Polyclonal ()
Application	Alternatives Western Blotting (WB) (23), (6), (2), (1)
	1 reference available