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Details for Product No. ABIN390636

Exportin 1, CRM1 Homolog (Yeast) (XPO1) (C-Term), (AA 817-846) antibody

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Antigen
Synonyms
Xpo, crm1, exportin-1, CRM1, emb, exp1, AA420417, Crm1, Exp1, CG13387, DCRM1, Dmel\\CG13387, Emb, XPO-1, XPO1, Xpo1, dCRM1, l(2)k16715, 18.m06600, DDBDRAFT_0183812, DDBDRAFT_0234066, DDB_0183812, DDB_ ... show more
Epitope
»Alternatives C-Term, AA 817-846
Reactivity
»Alternatives Human, Mouse (Murine)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN390636
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This XPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 817-846 AA from the C-terminal region of human XPO1.
Clone RB19972
Isotype Ig
Specificity This XPO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 824~854 amino acids from the C-terminal region of human XPO1.
Predicted Reactivity Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name XPO1
Background XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
Synonyms: Exportin-1, Exp1, Chromosome region maintenance 1 protein homolog, CRM1, XPO1
Molecular Weight 123386 DA
Gene ID 7514
UniProt O14980
Research Area Cancer, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Dong, Biswas, Chook: "Structural basis for assembly and disassembly of the CRM1 nuclear export complex." in: Nature structural & molecular biology, Vol. 16, Issue 5, pp. 558-60, 2009 (PubMed).

Alternatives for antigen "Exportin 1, CRM1 Homolog (Yeast) (XPO1)", type "Antibodies"
Hosts (46)
Reactivities (43), (36), (31), (24), (19), (17), (12), (3), (2), (1)
Applications (26), (20), (14), (10), (4), (3), (2), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (5), (4), (1), (1), (1), (1), (1)
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