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Details for Product No. ABIN390676

Mastermind-Like 3 (Drosophila) (MAML3) (C-Term), (AA 640-665) antibody

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Synonyms GDN, MAM2, CAGH3, ERDA3, MAM-2, TNRC3
»Alternatives C-Term, AA 640-665
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN390676
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This MAML3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-665 AA from the C-terminal region of human MAML3.
Clone RB18761
Isotype Ig
Specificity This MAML3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 645~675 amino acids from the C-terminal region of human MAML3.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name MAML3
Background MAML3 acts as a transcriptional coactivator for NOTCH proteins. The protein has been shown to amplify NOTCH-induced transcription of HES1.
Synonyms: Mastermind-like protein 3, Mam-3, KIAA1816, MAML3
Molecular Weight 121780 DA
Gene ID 55534
UniProt Q96JK9
Research Area Cancer, Transcription Factors, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Lin, Oyama, Nagase et al.: "Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling." in: The Journal of biological chemistry, Vol. 277, Issue 52, pp. 50612-20, 2002 (PubMed).

Tonon, Modi, Wu et al.: "t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway." in: Nature genetics, Vol. 33, Issue 2, pp. 208-13, 2003 (PubMed).

Alternatives for antigen "Mastermind-Like 3 (Drosophila) (MAML3)", type "Antibodies"
Hosts (22), (6)
Reactivities (28), (14), (13), (13), (13), (1), (1), (1)
Applications (13), (10), (8), (4), (3), (2), (2), (2)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (1), (1), (1), (1), (1)