Mastermind-Like 3 (Drosophila) (MAML3) (C-Term), (AA 640-665) antibody

Details for Product No. ABIN390676
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Antigen
Synonyms AV234550, BC049812, Mam-2, mKIAA1816, Glrp1, CAGH3, ERDA3, GDN, MAM-2, MAM2, TNRC3
Epitope
C-Term, AA 640-665
(5), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(29), (12), (12), (12), (12)
Host
Rabbit
(23), (6)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(13), (10), (7), (4), (3), (3), (2), (2), (1)
Pubmed 2 references available
Quantity 400 μL
Options
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Catalog No. ABIN390676
291.50 $
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Immunogen This MAML3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 640-665 AA from the C-terminal region of human MAML3.
Clone RB18761
Isotype Ig
Specificity This MAML3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 645~675 amino acids from the C-terminal region of human MAML3.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name MAML3
Background MAML3 acts as a transcriptional coactivator for NOTCH proteins. The protein has been shown to amplify NOTCH-induced transcription of HES1.
Synonyms: Mastermind-like protein 3, Mam-3, KIAA1816, MAML3
Molecular Weight 121780 DA
Gene ID 55534
UniProt Q96JK9
Research Area Cancer, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Mastermind-Like 3 (Drosophila) (MAML3) (C-Term), (AA 640-665) antibody Western blot analysis of MAML3 antibody (C-term) (ABIN390676) in Hela cell line lysates (35 µg/lane). MAML3 (arrow) was detected using the purified polyclonal antibody.
anti-Mastermind-Like 3 (Drosophila) (MAML3) (C-Term), (AA 640-665) antibody (2) MAML3 Antibody (C-term) (ABIN390676) immunohistochemistry analysis in formalin fixed and paraffin embedded human lymphnode followed by peroxidase conjugation of the secondary antibody and DAB staining
anti-Mastermind-Like 3 (Drosophila) (MAML3) (C-Term), (AA 640-665) antibody (3) MAML3 Antibody (C-term) (ABIN390676) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Lin, Oyama, Nagase et al.: "Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling." in: The Journal of biological chemistry, Vol. 277, Issue 52, pp. 50612-20, 2002 (PubMed).

Tonon, Modi, Wu et al.: "t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway." in: Nature genetics, Vol. 33, Issue 2, pp. 208-13, 2003 (PubMed).

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