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Details for Product No. ABIN391538

BCL6 Co-Repressor (BCOR) (AA 1107-1137), (Center), (Ser1122) antibody

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Synonyms ANOP2, MAA2, MCOPS2, RGD1562735, 5830466J11Rik, 8430401K06Rik, BcorR, D930024N20Rik, mKIAA1575, BCOR
»Alternatives AA 1107-1137, Center, Ser1122
»Alternatives Human, Mouse (Murine)
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN391538
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This BCOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1107-1137 AA from the Central region of human BCOR.
Clone RB19040
Isotype Ig
Specificity This BCOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1115~1144 amino acids from the Center region of human BCOR.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name BCOR
Background BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs.
Synonyms: BCL-6 corepressor, BCoR , KIAA1575, BCOR
Molecular Weight 192189 DA
Gene ID 54880
UniProt Q6W2J9
Research Area Apoptosis/Necrosis
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Hilton, Manson, Urquhart et al.: "Left-sided embryonic expression of the BCL-6 corepressor, BCOR, is required for vertebrate laterality determination." in: Human molecular genetics, Vol. 16, Issue 14, pp. 1773-82, 2007 (PubMed).

Ghetu, Corcoran, Cerchietti et al.: "Structure of a BCOR corepressor peptide in complex with the BCL6 BTB domain dimer." in: Molecular cell, Vol. 29, Issue 3, pp. 384-91, 2008 (PubMed).

Alternatives for antigen "BCL6 Co-Repressor (BCOR)", type "Antibodies"
Hosts (16), (6), (3)
Reactivities (24), (14), (2), (2), (1), (1)
Applications (21), (17), (10), (2), (2), (2), (2), (1), (1)
Epitopes (6), (3), (2), (1), (1)