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ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 1117-1145), (C-Term) antibody

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Synonyms EST170205, MOAT-B, MOATB, MRP4, D630049P08Rik, Mrp4
AA 1117-1145, C-Term
(23), (18), (9), (8), (7), (6), (5), (3), (2), (2), (2), (1), (1)
(105), (40), (32), (1), (1), (1), (1)
(48), (41), (17), (10)
Clonality (Clone)
Polyclonal ()
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Western Blotting (WB)
(91), (56), (38), (23), (15), (11), (9), (9), (6), (4), (2), (1)
Pubmed 3 references available
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Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This ABCC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1117-1145 AA from the C-terminal region of human ABCC4.
Clone RB17763
Isotype Ig
Specificity This ABCC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1124~1153 amino acids from the C-terminal region of human ABCC4.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name ABCC4 (ABCC4 Antibody Abstract)
Background ABCC4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined, however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions.
Synonyms: Multi-specific organic anion transporter B, MOAT-B, MRP/cMOAT-related ABC transporter, ATP-binding cassette sub-family C member 4, Multidrug resistance-associated protein 4, ABCC4, MRP4
Molecular Weight 149527 DA
Gene ID 10257
UniProt O15439
Research Area Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4) (AA 1117-1145), (C-Term) antibody (ABIN391639) Western blot analysis of anti-ABCC4 Antibody (C-term) (ABIN391639) in CEM cell line l...
Background publications Adachi, Sampath, Lan et al.: "Expression of MRP4 confers resistance to ganciclovir and compromises bystander cell killing." in: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38998-9004, 2002 (PubMed).

Lee, Belinsky, Bell et al.: "Isolation of MOAT-B, a widely expressed multidrug resistance-associated protein/canalicular multispecific organic anion transporter-related transporter." in: Cancer research, Vol. 58, Issue 13, pp. 2741-7, 1998 (PubMed).

Kool, de Haas, Scheffer et al.: "Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines." in: Cancer research, Vol. 57, Issue 16, pp. 3537-47, 1997 (PubMed).

Catalog No. ABIN391639
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