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ADAMTS13 antibody (AA 829-858)

ADAMTS13 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB18029 unconjugated
Catalog No. ABIN391641
  • Target See all ADAMTS13 Antibodies
    ADAMTS13 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))
    Binding Specificity
    • 15
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 829-858
    Reactivity
    • 69
    • 19
    • 3
    Human
    Host
    • 49
    • 9
    • 8
    • 3
    Rabbit
    Clonality
    • 53
    • 16
    Polyclonal
    Conjugate
    • 28
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAMTS13 antibody is un-conjugated
    Application
    • 44
    • 22
    • 13
    • 13
    • 10
    • 9
    • 9
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ADAMTS13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 829-858 amino acids from the Central region of human ADAMTS13.
    Clone
    RB18029
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    ADAMTS13 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))
    Alternative Name
    ADAMTS13 (ADAMTS13 Products)
    Synonyms
    ADAMTS13 antibody, ADAM-TS13 antibody, ADAMTS-13 antibody, C9orf8 antibody, VWFCP antibody, vWF-CP antibody, Gm710 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 13 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 13 antibody, ADAMTS13 antibody, Adamts13 antibody, adamts13 antibody
    Background
    ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.
    Molecular Weight
    153604
    Gene ID
    11093
    NCBI Accession
    NP_620594, NP_620595, NP_620596
    UniProt
    Q76LX8
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