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Details for Product No. ABIN391699

Growth Differentiation Factor 6 (GDF6) (C-Term), (AA 326-353) antibody

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Synonyms GDF6/7, BMP13, CDMP2, KFM, KFS, KFS1, KFSL, LCA17, MCOP4, MCOPCB6, SCDO4, SGM1, GDF16, gdf16, CDMP-2, gdf6, rdr, sb:cb278
»Alternatives C-Term, AA 326-353
»Alternatives Human, Mouse (Murine)
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Un-conjugated
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN391699
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This GDF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-353 AA from the C-terminal region of human GDF6.
Clone RB15615
Isotype Ig
Specificity This GDF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 333~362 amino acids from the C-terminal region of human GDF6.
Predicted Reactivity Cow (Bovine),Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name GDF6
Background GDF6 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily of secreted signaling molecules. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this protein result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), which is a congenital disorder of spinal segmentation.
Synonyms: Growth/differentiation factor 6, GDF-6, Growth/differentiation factor 16, GDF16, GDF6
Molecular Weight 50662 DA
Gene ID 392255
UniProt Q6KF10
Research Area Cell Signaling, Stem Cells, Neurology, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Tassabehji, Fang, Hilton et al.: "Mutations in GDF6 are associated with vertebral segmentation defects in Klippel-Feil syndrome." in: Human mutation, Vol. 29, Issue 8, pp. 1017-27, 2008 (PubMed).

Alternatives for antigen "Growth Differentiation Factor 6 (GDF6)", type "Antibodies"
Hosts (32)
Reactivities (30), (24), (18), (12), (12)
Applications (23), (13), (10), (6), (6), (4)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (10), (4), (2), (2), (1)