Cyclin-Dependent Kinase 15 (ALS2CR7) (N-Term), (AA 49-78) antibody

Details for Product No. ABIN391735
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Synonyms ALS2CR7, PFTAIRE2, PFTK2, Pftk2, Als2cr7, als2cr7, MGC146368, zgc:136819
N-Term, AA 49-78
(5), (2), (2), (1), (1), (1), (1)
(12), (5), (1)
(10), (3)
Clonality (Clone)
Polyclonal ()
Western Blotting (WB)
(13), (5), (2), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN391735
Quantity 400 µL
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Immunogen This ALS2CR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-78 AA from the N-terminal region of human ALS2CR7.
Clone RB3181
Isotype Ig
Specificity This ALS2CR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6~35 amino acids from the N-terminal region of human ALS2CR7.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ALS2CR7
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
Synonyms: Serine/threonine-protein kinase ALS2CR7, Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7
Molecular Weight 43574 DA
Gene ID 65061
UniProt Q96Q40
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure, Cell Cycle, Transcription Factors, Signaling, Metabolism
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Cyclin-Dependent Kinase 15 (ALS2CR7) (N-Term), (AA 49-78) antibody ALS2CR7 Antibody (R13) (ABIN391735) western blot analysis in A2058 cell line lysates (35 µg/lane).This demonstrates the ALS2CR7 antibody detected the ALS2CR7 protein (arrow).
Background publications Hadano, Hand, Osuga et al.: "A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2." in: Nature genetics, Vol. 29, Issue 2, pp. 166-73, 2001 (PubMed).

Hosts (10), (3)
Reactivities (12), (5), (1)
Applications (13), (5), (2), (2), (1)
Epitopes (5), (2), (2), (1), (1), (1), (1)
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