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Butyrylcholinesterase (BCHE) (AA 385-415), (Center) antibody

Details for Product No. ABIN392290
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Antigen
Synonyms che, che1, bche, cholinesterase, CHE1, CHE2, E1, C730038G20Rik
Epitope
AA 385-415, Center
(15), (12), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(68), (27), (27), (15), (13), (13), (13), (1)
Host
Rabbit
(51), (19)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application
Western Blotting (WB)
(41), (30), (18), (14), (10), (8), (4), (3), (3), (3), (3), (1), (1)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN392290
291.50 $
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Immunogen This BCHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 385-415 AA from the Central region of human BCHE.
Clone RB17724
Isotype Ig
Specificity This BCHE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 393~422 amino acids from the center region of human BCHE.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name BCHE
Background Mutant proteins of BCHE are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
Synonyms: Pseudocholinesterase, Butyrylcholine esterase, Choline esterase II, Acylcholine acylhydrolase, Cholinesterase, BCHE, CHE1
Molecular Weight 68418 DA
Gene ID 590
UniProt P06276
Research Area Metabolism, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Butyrylcholinesterase (BCHE) (AA 385-415), (Center) antibody Western blot analysis of anti-BCHE Antibody (Center)(ABIN392290) in A2058 cell line lysates (35 µg/lane). BCHE (arrow) was detected using the purified polyclonal antibody.
Background publications Primo-Parmo, Bartels, Wiersema et al.: "Characterization of 12 silent alleles of the human butyrylcholinesterase (BCHE) gene." in: American journal of human genetics, Vol. 58, Issue 1, pp. 52-64, 1996 (PubMed).

Validation Images
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