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Details for Product No. ABIN392301

seryl-tRNA Synthetase 2, Mitochondrial (SARS2) (AA 315-344), (Center) antibody

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Synonyms SARS, SARSM, SERS, SYS, SerRS, SerRSmt, mtSerRS, D7Ertd353e, 2410015F05Rik
»Alternatives AA 315-344, Center
»Alternatives Human
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 3 references available
Catalog no. ABIN392301
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This SARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-344 AA from the Central region of human SARS2.
Clone RB14863
Isotype Ig
Specificity This SARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322~352 amino acids from the center region of human SARS2.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name SARS2
Background SARS2 catalyzes the attachment of serine to tRNA(Ser). It is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
Synonyms: Seryl-tRNA synthetase, mitochondrial [Precursor], EC, Seryl-tRNA(Ser/Sec) synthetase, Serine--tRNA ligase, SerRSmt, SARS2, SARSM
Molecular Weight 58283 DA
Gene ID 54938
UniProt Q9NP81
Research Area Metabolism, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Yokogawa, Shimada, Takeuchi et al.: "Characterization and tRNA recognition of mammalian mitochondrial seryl-tRNA synthetase." in: The Journal of biological chemistry, Vol. 275, Issue 26, pp. 19913-20, 2000 (PubMed).

Gibbons, Yan, Li et al.: "Genomic organization, expression, and subcellular localization of mouse mitochondrial seryl-tRNA synthetase." in: Biochemical and biophysical research communications, Vol. 317, Issue 3, pp. 774-8, 2004 (PubMed).

Müller, Deschauer, Neudecker et al.: "Late-onset mitochondrial myopathy with dystrophic changes due to a G7497A mutation in the mitochondrial tRNA(Ser(UCN)) gene." in: Acta neuropathologica, Vol. 110, Issue 4, pp. 426-30, 2005 (PubMed).

Alternatives for antigen "seryl-tRNA Synthetase 2, Mitochondrial (SARS2)", type "Antibodies"
Hosts (12), (1)
Reactivities (12), (2), (2), (1)
Applications (12), (5), (3), (2), (1)
Epitopes (5), (2), (2), (1), (1), (1), (1)