Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3) (N-Term), (AA 24-51) antibody

Details for Product No. ABIN392316
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Antigen
Synonyms RALDH3, ALDH1A3, ALDH1A6, ALDH6, MCOP8, Aldh6, V1
Epitope
N-Term, AA 24-51
(3), (2), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(15), (4), (1)
Host
Rabbit
(12), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(15), (9), (6), (4), (3), (2), (1), (1)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN392316
238.50 $
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Immunogen This ALDH1A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-51 AA from the N-terminal region of human ALDH1A3.
Clone RB16818
Isotype Ig
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name ALDH1A3
Background Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme ALDH1A3 uses retinal as a substrate, either in a free or cellular retinol-binding protein form.

Synonyms: Retinaldehyde dehydrogenase 3, Aldehyde dehydrogenase 6, Aldehyde dehydrogenase family 1 member A3, ALDH1A3, ALDH6
Molecular Weight 56108 Da
Gene ID 220
UniProt P47895
Research Area Metabolism, Cell Structure
Application Notes Suggested dilutions:
WB = 1:1000, IHC = 1:10-50
Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
Expiry Date 6 months
Supplier Images
anti-Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3) (N-Term), (AA 24-51) antibody Western blot analysis of anti-ALDH1A3 Antibody (N-term) (ABIN392316) in mouse kidney tissue lysates (35 µg/lane). ALDH1A3(arrow) was detected using the purified polyclonal antibody.
anti-Aldehyde Dehydrogenase 1 Family, Member A3 (ALDH1A3) (N-Term), (AA 24-51) antibody (2) Formalin-fixed and paraffin-embedded human kideny tissue reacted with ALDH1A3 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Background publications Yoshida, Rzhetsky, Hsu et al.: "Human aldehyde dehydrogenase gene family." in: European journal of biochemistry / FEBS, Vol. 251, Issue 3, pp. 549-57, 1998 (PubMed).

Rexer, Zheng, Ong: "Retinoic acid biosynthesis by normal human breast epithelium is via aldehyde dehydrogenase 6, absent in MCF-7 cells." in: Cancer research, Vol. 61, Issue 19, pp. 7065-70, 2001 (PubMed).

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