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Details for Product No. ABIN392465

Glycyl-tRNA Synthetase (GARS) (C-Term), (AA 706-739) antibody

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Antigen
Synonyms HMN5, CMT2D, DSMAV, GlyRS, SMAD1, RGD1559871, GENA202, Gena201, Nmf249, Sgrp23, fb02f03, si:dkey-276i5.1, wu:fb02f03, Aat-gly, CG6778, Dmel\\CG6778, GRS, gars, team, GB13467, MGC79495
Epitope
»Alternatives C-Term, AA 706-739
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN392465
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This GARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 706-739 AA from the C-terminal region of human GARS.
Clone RB11217
Isotype Ig
Specificity This GARS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GARS.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name GARS
Background GARS is a glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. This protein is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. The protein has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Synonyms: Glycyl-tRNA synthetase, Glycyl-tRNA synthetase, Glycine--tRNA ligase, GlyRS, GARS
Molecular Weight 83140 DA
Gene ID 2617
UniProt NP_002038
Research Area Metabolism, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.44 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Shiba, Schimmel, Motegi et al.: "Human glycyl-tRNA synthetase. Wide divergence of primary structure from bacterial counterpart and species-specific aminoacylation." in: The Journal of biological chemistry, Vol. 269, Issue 47, pp. 30049-55, 1994 (PubMed).

Antonellis, Ellsworth, Sambuughin et al.: "Glycyl tRNA synthetase mutations in Charcot-Marie-Tooth disease type 2D and distal spinal muscular atrophy type V." in: American journal of human genetics, Vol. 72, Issue 5, pp. 1293-9, 2003 (PubMed).

Alternatives for antigen "Glycyl-tRNA Synthetase (GARS)", type "Antibodies"
Hosts (22), (1)
Reactivities (23), (15), (3), (1), (1), (1), (1)
Applications (14), (10), (6), (4), (2), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (2), (1), (1), (1)
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