Diacylglycerol Kinase, delta 130kDa (DGKD) (C-Term), (AA 1061-1091) antibody

Details for Product No. ABIN392725
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Antigen
Synonyms DGKdelta, dgkd-2, AI841987, D330025K09, RGD1563309
Epitope
C-Term, AA 1061-1091
(11), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(26), (3)
Host
Rabbit
(27)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(27), (16), (8), (4), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN392725
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This DGKD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1061-1091 AA from the C-terminal region of human DGKD.
Clone RB3865
Isotype Ig
Specificity This DGKD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1050~1079 amino acids from the C-terminal region of human DGKD.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DGKD
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA &
Synonyms: Diacylglycerol kinase delta, Diglyceride kinase, DAG kinase delta, 130 kDa diacylglycerol kinase
Molecular Weight 132825 DA
Gene ID 8527
UniProt Q16760
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Cycle, Transcription Factors, Signaling, Metabolism, Cell Structure
Application Notes WB = 1:1000, IHC = 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Diacylglycerol Kinase, delta 130kDa (DGKD) (C-Term), (AA 1061-1091) antibody Western blot analysis of anti-anti-DGK delta Pab (ABIN392725) in Jurkat cell line lysates (35 µg/lane). DGK delta (arrow) was detected using the purified polyclonal antibody.
anti-Diacylglycerol Kinase, delta 130kDa (DGKD) (C-Term), (AA 1061-1091) antibody (2) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma
Background publications Sakane, Imai, Kai et al.: "Molecular cloning of a novel diacylglycerol kinase isozyme with a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein-tyrosine kinases." in: The Journal of biological chemistry, Vol. 271, Issue 14, pp. 8394-401, 1996 (PubMed).

Hosts (27)
Reactivities (26), (3)
Applications (27), (16), (8), (4), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1)
Epitopes (11), (2), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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