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Details for Product No. ABIN392828

Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (N-Term), (AA 234-265) antibody

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Antigen
Synonyms Pcptp1, ec-ptp, pcptp1, ptp-sl, ptpbr7, PCPTP1, EC-PTP, PTP-SL, PTPBR7, PTPRQ, Gmcp1, RPTPRR, mPTP213, PTPRR
Epitope
»Alternatives N-Term, AA 234-265
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 2 references available
Catalog no. ABIN392828
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This PCPTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-265 AA from the N-terminal region of human PCPTP1.
Clone RB0621
Isotype Ig
Specificity This PCPTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242~272 amino acids from the N-terminal region of human PCPTP1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name PCPTP1
Background PCPTP1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene for this protein predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of the gene for this protein was reported to be regulated by the nerve growth factor, which suggested a function in neuronal growth and differentiation.
Molecular Weight 73862 DA
Gene ID 5801
UniProt Q15256
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure, Cancer, Cell Cycle, Neurology
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Ogata, Sawada, Fujino et al.: "cDNA cloning and characterization of a novel receptor-type protein tyrosine phosphatase expressed predominantly in the brain." in: The Journal of biological chemistry, Vol. 270, Issue 5, pp. 2337-43, 1995 (PubMed).

Blanco-Aparicio, Torres, Pulido: "A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase." in: The Journal of cell biology, Vol. 147, Issue 6, pp. 1129-36, 2000 (PubMed).

Alternatives for antigen "Protein tyrosine Phosphatase, Receptor Type, R (PTPRR)", type "Antibodies"
Hosts (43), (5)
Reactivities (43), (23), (21), (19), (18), (17), (2), (2), (1)
Applications (27), (15), (15), (13), (10), (4), (2), (1), (1), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (7), (3), (2), (2), (2), (1), (1)
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