Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (N-Term), (AA 234-265) antibody

Details for Product No. ABIN392828
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms Pcptp1, ec-ptp, pcptp1, ptp-sl, ptpbr7, PCPTP1, EC-PTP, PTP-SL, PTPBR7, PTPRQ, Gmcp1, RPTPRR, mPTP213, PTPRR
Epitope
N-Term, AA 234-265
(7), (3), (2), (2), (2), (1), (1)
Reactivity
Human
(44), (24), (22), (19), (18), (17), (2), (2), (1)
Host
Rabbit
(44), (5)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC)
(28), (15), (14), (13), (10), (4), (2), (2), (2), (1), (1)
Pubmed 2 references available
Catalog no. ABIN392828
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This PCPTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-265 AA from the N-terminal region of human PCPTP1.
Clone RB0621
Isotype Ig
Specificity This PCPTP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242~272 amino acids from the N-terminal region of human PCPTP1.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name PCPTP1
Background PCPTP1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domains, and thus represents a receptor-type PTP. The similar gene for this protein predominately expressed in mouse brain was found to associate with, and thus regulate the activity and cellular localization of MAP kinases. The rat counterpart of the gene for this protein was reported to be regulated by the nerve growth factor, which suggested a function in neuronal growth and differentiation.
Molecular Weight 73862 DA
Gene ID 5801
UniProt Q15256
Research Area Phospho-specific antibodies, Cell Signaling, Protein Modifications, Cell Structure, Cancer, Cell Cycle, Neurology
Application Notes WB = 1:1000, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (N-Term), (AA 234-265) antibody The anti-PCPTP1 Pab (ABIN392828) is used in Western blot to detect PCPTP1 in placenta tissue lysate.
anti-Protein tyrosine Phosphatase, Receptor Type, R (PTPRR) (N-Term), (AA 234-265) antibody (2) Formalin-fixed and paraffin-embedded human brain tissue reacted with hPCPTP1-Y249, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Background publications Ogata, Sawada, Fujino et al.: "cDNA cloning and characterization of a novel receptor-type protein tyrosine phosphatase expressed predominantly in the brain." in: The Journal of biological chemistry, Vol. 270, Issue 5, pp. 2337-43, 1995 (PubMed).

Blanco-Aparicio, Torres, Pulido: "A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase." in: The Journal of cell biology, Vol. 147, Issue 6, pp. 1129-36, 2000 (PubMed).

Hosts (44), (5)
Reactivities (44), (24), (22), (19), (18), (17), (2), (2), (1)
Applications (28), (15), (14), (13), (10), (4), (2), (2), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (7), (3), (2), (2), (2), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
back to top