One Cut Homeobox 2 (ONECUT2) (N-Term) antibody

Details for Product No. ABIN405112
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Antigen
Synonyms OC-2, OC2, C730009D12, Oc2, RGD1564677
Epitope
N-Term
(3), (2), (2), (2), (1)
Reactivity
Mouse (Murine), Human
(8), (2), (1), (1), (1)
Host
Rabbit
(8)
Clonality
Polyclonal
Application
Western Blotting (WB)
(8), (2)
Pubmed 1 reference available
Catalog no. ABIN405112
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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  • +1 404 474 4654
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Immunogen Synthetic peptide directed towards the N terminal of human ONECUT2
Sequence TSMASILDGGDYRPELSIPLHHAMSMSCDSSPPGMGMSNT YTTLTPLQPL
Predicted Reactivity Guinea pig : 100 %, Pig : 100 %, Mouse : 90 %
Characteristics This is a rabbit polyclonal antibody against ONECUT2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ONECUT2
Background ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism. This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.
Molecular Weight 54 kDa
Gene ID 9480
NCBI Accession NM_004852, NP_004843
UniProt O95948
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 504 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-One Cut Homeobox 2 (ONECUT2) (N-Term) antibody WB Suggested Anti-ONECUT2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: 721_B cell lysate
Background publications Rauch, Li, Wu et al.: "MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells." in: Cancer research, Vol. 66, Issue 16, pp. 7939-47, 2006 (PubMed).

Hosts (8)
Reactivities (8), (2), (1), (1), (1)
Applications (8), (2)
Epitopes (3), (2), (2), (2), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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