One Cut Homeobox 2 (ONECUT2) (N-Term) antibody

Details for Product No. ABIN405112
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Synonyms C730009D12, OC-2, Oc2, OC2, RGD1564677
(16), (15), (2), (2), (1)
Human, Mouse (Murine)
(24), (3), (2), (1), (1)
(2), (2), (2), (2), (2), (2)
Western Blotting (WB)
(23), (13), (3), (3)
Pubmed 1 reference available
Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the N terminal of human ONECUT2
Predicted Reactivity Guinea pig : 100 %, Pig : 100 %, Mouse : 90 %
Characteristics This is a rabbit polyclonal antibody against ONECUT2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ONECUT2 (ONECUT2 Antibody Abstract)
Background ONECUT2 is a member of the transcription factors of the ONECUT class, whose prototype is hepatocyte nuclear factor (HNF)-6. The distribution of OC-2 mRNA in humans is tissue-restricted, the strongest expression being detected in the liver and skin. ONECUT2 participates in the network of transcription factors required for liver differentiation and metabolism. This gene encodes a member of the onecut family of transcription factors, which are characterized by a cut domain and an atypical homeodomain. The protein binds to specific DNA sequences and stimulates expression of target genes, including genes involved in melanocyte and hepatocyte differentiation.
Molecular Weight 54 kDa
Gene ID 9480
NCBI Accession NP_004843, NM_004852
UniProt O95948
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 504 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-One Cut Homeobox 2 (ONECUT2) (N-Term) antibody (ABIN405112) WB Suggested Anti-ONECUT2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: <...
Background publications Rauch, Li, Wu et al.: "MIRA-assisted microarray analysis, a new technology for the determination of DNA methylation patterns, identifies frequent methylation of homeodomain-containing genes in lung cancer cells." in: Cancer research, Vol. 66, Issue 16, pp. 7939-47, 2006 (PubMed).

Catalog No. ABIN405112
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