SIX Homeobox 2 (SIX2) (N-Term) antibody

Details for Product No. ABIN405210
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Antigen
Synonyms six1b, six2, zgc:92332, six2-A
Epitope
N-Term
(7), (7), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Xenopus laevis, Dog (Canine), Cow (Bovine), Zebrafish (Danio rerio), Pig (Porcine), Human, Chicken
(32), (15), (14), (12), (12)
Host
Rabbit
(28), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(22), (13), (10), (3), (3), (2), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN405210
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human SIX2
Sequence WSLPACEHLH KNESVLKAKA VVAFHRGNFR ELYKILESHQ FSPHNHAKLQ
Predicted Reactivity African clawed frog : 100 %, Chicken : 100 %, Dog : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 100 %
Characteristics This is a rabbit polyclonal antibody against SIX2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SIX2
Background This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. SIX2 is a transcription factor which, like other members of this gene family, may be involved in limb or eye development.
Molecular Weight 32 kDa
Gene ID 10736
NCBI Accession NP_058628, NM_016932
UniProt Q9NPC8
Research Area Organogenesis, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 291 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Weber, Taylor, Winyard et al.: "SIX2 and BMP4 mutations associate with anomalous kidney development." in: Journal of the American Society of Nephrology : JASN, Vol. 19, Issue 5, pp. 891-903, 2008 (PubMed).

Validation Images
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