Pyruvate Dehydrogenase beta (PDHB) (N-Term) antibody

Details for Product No. ABIN405971, Supplier: Login to see New
New
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms CG 11876, Dmel\\CG11876, E1beta, PDHB, zgc:64062, wu:fc76a05, PDHBD, PDHE1-B, PHE1B, 2610103L06Rik, AL024199, C81408
Epitope
N-Term
(6), (6), (6), (4), (3), (2), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Fruit Fly (Drosophila melanogaster), Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
(43), (28), (22)
Host
Rabbit
(41), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(33), (17), (11), (10), (9), (4), (4), (3), (1)
Pubmed 1 reference available
Supplier Login to see New
Catalog number from supplier Login to see New
Quantity 50 μg
Options
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the N terminal of human PDHB
Blocking Peptide Blocking peptide for this product available: Pyruvate Dehydrogenase beta (PDHB) (N-Term) peptide (ABIN981529)
Sequence GLWKKYGDKR IIDTPISEMG FAGIAVGAAM AGLRPICEFM TFNFSMQAID
Predicted Reactivity Chicken : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Pig : 100 %, Rabbit : 100 %, Zebrafish : 90 %, African clawed frog : 70 %, Yeast : 70 %
Characteristics This is a rabbit polyclonal antibody against PDHB. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PDHB (PDHB Antibody Abstract)
Background The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
Molecular Weight 39 kDa
Gene ID 5162
NCBI Accession NM_000925, NP_000916
UniProt P11177
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 359 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Pyruvate Dehydrogenase beta (PDHB) (N-Term) antibody (ABIN405971) anti-Pyruvate Dehydrogenase beta (PDHB) (N-Term) antibody
Background publications Okajima, Korotchkina, Prasad et al.: "Mutations of the E1beta subunit gene (PDHB) in four families with pyruvate dehydrogenase deficiency." in: Molecular genetics and metabolism, Vol. 93, Issue 4, pp. 371-80, 2008 (PubMed).

Catalog No. ABIN405971
$289.00
Plus shipping costs $45.00

Order hotline:

  • +1 877 302 8632
  • +1 888 205 9894 (TF)