ADP-Ribosylation Factor-Like 13B (ARL13B) (Middle Region) antibody

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Antigen
Synonyms ARL2L1, MGC185757, arl2l1, chunp6872, fc23g07, wu:fc23g07, zgc:123149, JBTS8, A530097K21Rik, A930014M17Rik, Arl2l1, C530009C10Rik, hnn
Epitope
Middle Region
(4), (3), (2), (2), (2), (1), (1)
Reactivity
Human, Mouse (Murine), Zebrafish (Danio rerio)
(21), (5), (5), (2)
Host
Rabbit
(19), (4)
Clonality
Polyclonal
Application
Western Blotting (WB)
(21), (8), (6), (3), (2), (1), (1), (1)
Pubmed 2 references available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human ARL13B
Blocking Peptide Blocking peptide for this product available: ADP-Ribosylation Factor-Like 13B (ARL13B) (Middle Region) peptide (ABIN973421)
Sequence VEPLNIDDCA PESPTPPPPP PPVGWGTPKV TRLPKLEPLG ETHHNDFYRK
Predicted Reactivity Guinea pig : 100 %, Human : 100 %, Chicken : 90 %, Dog : 90 %, Mouse : 90 %, Horse : 70 %, Zebrafish : 70 %
Characteristics This is a rabbit polyclonal antibody against ARL13B. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ARL13B (ARL13B Antibody Abstract)
Background ARL13B has an evolutionarily conserved role mediating cilia function in multiple organs. N and C domains of ARL13B cooperatively regulate its ciliary localization and that N domain-dependent self-association of Arl13b may be important for its function in cilia biogenesis.
Molecular Weight 36 kDa
Gene ID 200894
NCBI Accession NM_144996, NP_659433
UniProt Q8TCL5
Research Area Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 321 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-ADP-Ribosylation Factor-Like 13B (ARL13B) (Middle Region) antibody (ABIN406263) WB Suggested Anti-ARL13B Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Product cited in: Zhang, Wlodarczyk, Niederreither et al.: "Fuz regulates craniofacial development through tissue specific responses to signaling factors." in: PLoS ONE, Vol. 6, Issue 9, pp. e24608, 2011 (PubMed).

Background publications Fan, Esmail, Ansley et al.: "Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome." in: Nature genetics, Vol. 36, Issue 9, pp. 989-93, 2004 (PubMed).

Catalog No. ABIN406263
$289.00
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