MPP7 antibody (N-Term)
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- Target See all MPP7 Antibodies
- MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Horse, Rabbit, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MPP7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MPALSTGSGS DTGLYELLAA LPAQLQPHVD SQEDLTFLWD MFGEKSLHSL
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against MPP7. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MPP7
- Top Product
- Discover our top product MPP7 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 576 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation." in: Molecular biology of the cell, Vol. 18, Issue 5, pp. 1744-55, (2007) (PubMed).
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The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation." in: Molecular biology of the cell, Vol. 18, Issue 5, pp. 1744-55, (2007) (PubMed).
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- Target
- MPP7 (Membrane Protein, Palmitoylated 7 (MAGUK p55 Subfamily Member 7) (MPP7))
- Alternative Name
- MPP7 (MPP7 Products)
- Synonyms
- 1110068J02Rik antibody, 2810038M04Rik antibody, 5430426E14Rik antibody, AI415104 antibody, Gm955 antibody, dlg3 antibody, hmp antibody, membrane palmitoylated protein 7 antibody, membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) antibody, membrane protein, palmitoylated 7a (MAGUK p55 subfamily member 7) antibody, MPP7 antibody, Mpp7 antibody, mpp7a antibody
- Background
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MPP7 acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. MPP7 is involved in the assembly of protein complexes at sites of cell-cell contact.Membrane-associated guanylate kinases (MAGUKs) are important adaptor proteins involved in the assembly of protein complexes at sites of cell-cell contact. They are found in synapses, adherens junctions, and tight junctions. All MAGUKs contain at least 1 PDZ domain, an SH3 domain, and a GUK domain, and many contain 1 or 2 L27 domains, which are involved in multimerization of MAGUKs. MPP7 belongs to the p55 stardust subfamily of MAGUKs, which is named for a Drosophila gene required for establishment of cell polarity in the developing fly embryo (Bohl et al., 2007 [PubMed 17237226]).[supplied by OMIM].
Alias Symbols: FLJ32798, RP11-218D6.5
Protein Interaction Partner: AMOT, Wwtr1, Yap1, UBC,
Protein Size: 576 - Molecular Weight
- 65 kDa
- Gene ID
- 143098
- NCBI Accession
- NM_173496, NP_775767
- UniProt
- Q5T2T1
- Pathways
- Cell-Cell Junction Organization
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