Inositol-Tetrakisphosphate 1-Kinase (ITPK1) (N-Term) antibody

Details for Product No. ABIN406459
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms Temt, wu:fj15d08, zgc:56075, BC031182, ITRPK1
Epitope
N-Term
(9), (9), (5), (5), (2), (1), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Pig (Porcine), Cow (Bovine), Zebrafish (Danio rerio), Xenopus laevis, Human
(42), (16), (3)
Host
Rabbit
(40), (4)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(44), (21), (4), (4), (3), (2), (2), (1)
Pubmed 1 reference available
Quantity 50 µg
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN406459
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the N terminal of human ITPK1
Sequence MEVVQLNLSRPIEEQGPLDVIIHKLTDVILEADQNDSQSL ELVHRFQEYI
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, African clawed frog : 70 %
Characteristics This is a rabbit polyclonal antibody against ITPK1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ITPK1
Background ITPK1 is the kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. It may also act as an isomerase that interconverts the inositol tetraphosphate isomers Ins(1,3,4,5)P4 and Ins(1,3,4,6)P4 in the presence of ADP and magnesium. It probably acts as the rate-limiting enzyme of the InsP6 pathway. ITPK1 modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.
Molecular Weight 45 kDa
Gene ID 3705
NCBI Accession NM_014216, NP_055031
UniProt Q13572
Research Area Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 414 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Inositol-Tetrakisphosphate 1-Kinase (ITPK1) (N-Term) antibody WB Suggested Anti-ITPK1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human heart
Background publications Chamberlain, Qian, Stiles et al.: "Integration of inositol phosphate signaling pathways via human ITPK1." in: The Journal of biological chemistry, Vol. 282, Issue 38, pp. 28117-25, 2007 (PubMed).

Validation Images
back to top