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Ribonucleotide Reductase M2 (RRM2) (Middle Region) antibody

Details for Product No. ABIN453352, Supplier: Login to see New
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Synonyms RRM2, rrm2, rr2m, R2, RR2, RR2M, AA407299, cb111, chunp6884, r2
Middle Region
(6), (6), (4), (4), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1)
(65), (23), (23), (2), (1), (1), (1), (1)
(50), (14), (3)
(3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(50), (20), (14), (14), (12), (11), (4), (1), (1), (1)
Pubmed 2 references available
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Quantity 0.4 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide selected from the Center region of human RRM2
Specificity This antibody reacts to RRM2.
Purification Saturated Ammonium Sulfate (SAS) precipitation
Alternative Name RRM2 / RR2 (RRM2 Antibody Abstract)
Background RRM2 is one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the protein (M2) is regulated in a cell-cycle dependent fashion.Synonyms: Ribonucleoside-diphosphate reductase subunit M2, Ribonucleotide reductase small chain, Ribonucleotide reductase small subunit
Gene ID 6241
NCBI Accession NP_001025
UniProt P31350
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-Ribonucleotide Reductase M2 (RRM2) (Middle Region) antibody (ABIN453352) Western blot analysis of RRM2 antibody (Center) in Jurkat cell line lysates (35ug/lan...
Background publications Liu, Xue, Yen: "Redox property of ribonucleotide reductase small subunit M2 and p53R2." in: Methods in molecular biology (Clifton, N.J.), Vol. 477, pp. 195-206, 2008 (PubMed).

Kolesar, Huang, Eickhoff et al.: "Evaluation of mRNA by Q-RTPCR and protein expression by AQUA of the M2 subunit of ribonucleotide reductase (RRM2) in human tumors." in: Cancer chemotherapy and pharmacology, Vol. 64, Issue 1, pp. 79-86, 2009 (PubMed).

Catalog No. ABIN453352
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