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Details for Product No. ABIN453749

Mitochondrial Amidoxime Reducing Component 2 (MARC2) (C-Term) antibody

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Antigen
Synonyms MOSC2, RP11-270A6.1, 2810484M10Rik, Mosc2, mARC1, Mg87, mARC2
Epitope
»Alternatives C-Term
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives ELISA, Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN453749
Quantity 0.4 mL
Price
346.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen KLH conjugated synthetic peptide selected from the C-terminal region of human MOSC2
Specificity This antibody reacts to MOSC2.
Purification Affinity chromatography on Protein A
Alternative Name MOSC2
Background Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex.
Alternate names: MOSC domain-containing protein 2, mitochondrial
Gene ID 54996
NCBI Accession NP_060368
UniProt Q969Z3
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09% (w/v) sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Simpson, Wellenreuther, Poustka et al.: "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing." in: EMBO reports, Vol. 1, Issue 3, pp. 287-92, 2001 (PubMed).

Havemeyer, Bittner, Wollers et al.: "Identification of the missing component in the mitochondrial benzamidoxime prodrug-converting system as a novel molybdenum enzyme." in: The Journal of biological chemistry, Vol. 281, Issue 46, pp. 34796-802, 2006 (PubMed).

Alternatives for antigen "Mitochondrial Amidoxime Reducing Component 2 (MARC2)", type "Antibodies"
Hosts (9)
Reactivities (7), (3)
Applications (9), (3), (3), (1), (1)
Epitopes (8), (2), (2), (1), (1), (1)
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