serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (N-Term) antibody

Details for Product No. ABIN487126
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Antigen
Synonyms SPINK1, Psti, Spink3, PCTT, PSTI, TATI, TCP, Psti-1, Spink1, Tilp
Epitope
N-Term
(4), (2), (1), (1), (1)
Reactivity
Human
(35), (16), (5)
Host
Rabbit
(40), (7), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(29), (20), (17), (8), (5), (4), (2), (1), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN487126
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human SPINK1
Sequence KVTGIFLLSA LALLSLSGNT GADSLGREAK CYNELNGCTK IYDPVCGTDG
Predicted Reactivity Human : 100 %, Rabbit : 90 %
Characteristics This is a rabbit polyclonal antibody against SPINK1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SPINK1
Background SPINK1 is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.
Molecular Weight 8 kDa
Gene ID 6690
NCBI Accession NP_003113, NM_003122
UniProt P00995
Research Area Proteolysis / Ubiquitin
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 79 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) (N-Term) antibody WB Suggested Anti-SPINK1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: MCF7 cell lysate
Product cited in: Tomlins, Rhodes, Yu et al.: "The role of SPINK1 in ETS rearrangement-negative prostate cancers." in: Cancer cell, Vol. 13, Issue 6, pp. 519-28, 2008 (PubMed).

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