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Potassium Channel Tetramerisation Domain Containing 15 (KCTD15) (AA 1-234), (N-Term) antibody

Details for Product No. ABIN487356, Supplier: Log in to see
Antigen
  • BC031749
  • kctd15
  • zgc:100865
Epitope
AA 1-234, N-Term
27
15
7
4
2
1
1
1
Reactivity
Human
58
21
19
1
1
1
1
1
Host
Mouse
44
14
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
51
35
16
10
6
2
Supplier
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Immunogen Recombinant human KCTD15 (1-234aa) purified from E. coli
Clone AT4C3
Isotype IgG3
Specificity The antibody recognizes human KCTD15. Other species not tested.
Characteristics Synonyms: KCTD15, KCTD-15, BTB/POZ domain-containing protein KCTD15
Purification Protein-G affinity chromatography
Alternative Name KCTD15
Background KCTD15 (Potassium channel tetramerisation domain containing 15, also known as BTB/POZ domain-containing protein KCTD15) is protein that in humans is encoded by the KCTD15 gene. KCTD15 is expressed at high level in brain and hypothalamus. The potassium channel KCTD15 was identified as a genetic loci associated with higher than normal body mass index (BMI) in humans along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. Single nucleotide polymorphisms (SNPs) in non-diabetic and diabetic patients showed that FTO was most strongly associated with obesity while MTCH2 and GNPDA2 were still significantly associated with higher than normal BMI levels.Synonyms: BTB/POZ domain-containing protein KCTD15, KCTD-15, KCTD15
Gene ID 79047
UniProt Q96SI1
Research Area Signaling, Metabolism, Transporters
Pathways
Application Notes ELISA. Western blot (1: 250 - 1: 1000). Immunofluorescence (1: 250 - 1: 500).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-Potassium Channel Tetramerisation Domain Containing 15 (KCTD15) (AA 1-234), (N-Term) antibody (ABIN487356) anti-Potassium Channel Tetramerisation Domain Containing 15 (KCTD15) (AA 1-234), (N-Term) antibody
Immunofluorescence (IF) image for anti-Potassium Channel Tetramerisation Domain Containing 15 (KCTD15) (AA 1-234), (N-Term) antibody (ABIN487356) anti-Potassium Channel Tetramerisation Domain Containing 15 (KCTD15) (AA 1-234), (N-Term) antibody (Image 2)
Western Blotting (WB) image for anti-Potassium Channel Tetramerisation Domain Containing 15 (KCTD15) (AA 1-234), (N-Term) antibody (ABIN487356) anti-Potassium Channel Tetramerisation Domain Containing 15 (KCTD15) (AA 1-234), (N-Term) antibody (Image 3)
Immunofluorescence (IF) image for anti-Potassium Channel Tetramerisation Domain Containing 15 (KCTD15) (AA 1-234), (N-Term) antibody (ABIN487356) anti-Potassium Channel Tetramerisation Domain Containing 15 (KCTD15) (AA 1-234), (N-Term) antibody (Image 4)
Background publications Elks, Loos, Sharp et al.: "Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth." in: PLoS medicine, Vol. 7, Issue 5, pp. e1000284, 2010 (PubMed).

Newton-Cheh, Johnson, Gateva et al.: "Genome-wide association study identifies eight loci associated with blood pressure." in: Nature genetics, Vol. 41, Issue 6, pp. 666-76, 2010 (PubMed).

Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).