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Details for Product No. ABIN487356

Potassium Channel Tetramerisation Domain Containing 15 (KCTD15) (AA 1-234), (N-Term) antibody

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Antigen
Synonyms BC031749, kctd15, zgc:100865
Epitope
»Alternatives AA 1-234, N-Term
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Application
»Alternatives ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN487356
Quantity 0.1 mL
Price
401.50 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 6 to 8 Business Days
Immunogen Recombinant human KCTD15 (1-234aa) purified from E. coli
Clone AT4C3
Isotype IgG3
Characteristics Synonyms: KCTD15, KCTD-15, BTB/POZ domain-containing protein KCTD15
Purification Protein-G affinity chromatography
Alternative Name KCTD15
Background KCTD15 (Potassium channel tetramerisation domain containing 15, also known as BTB/POZdomain-containing protein KCTD15) is protein that in humans is encoded by the KCTD15gene. KCTD15 is expressed at high level in brain and hypothalamus. The potassiumchannel KCTD15 was identified as a genetic loci associated with higher than normal bodymass index (BMI) in humans along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. Single nucleotide polymorphisms (SNPs) in non-diabetic and diabetic patients showedthat FTO was most strongly associated with obesity while MTCH2 and GNPDA2 were stillsignificantly associated with higher than normal BMI levels.
Gene ID 79047
UniProt Q96SI1
Research Area Signaling, Metabolism, Transporters
Application Notes ELISA. Western blot (1: 250 - 1: 1000). Immunofluorescence (1: 250 - 1: 500). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09% sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°Cfor longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Expiry Date 12 months
Background publications Strausberg, Feingold, Grouse et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, 2002 (PubMed).

Newton-Cheh, Johnson, Gateva et al.: "Genome-wide association study identifies eight loci associated with blood pressure." in: Nature genetics, Vol. 41, Issue 6, pp. 666-76, 2010 (PubMed).

Elks, Loos, Sharp et al.: "Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth." in: PLoS medicine, Vol. 7, Issue 5, pp. e1000284, 2010 (PubMed).

Alternatives for antigen "Potassium Channel Tetramerisation Domain Containing 15 (KCTD15)", type "Antibodies"
Hosts (18), (9)
Reactivities (29), (14), (13), (1), (1), (1), (1), (1)
Applications (27), (17), (11), (7), (5), (1), (1)
Epitopes (11), (3), (3), (2), (1)
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