Cytokine Receptor-Like Factor 1 (CRLF1) (Middle Region) antibody

Details for Product No. ABIN501581
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Antigen
Synonyms CRLF1, CISS, CISS1, CLF, CLF-1, NR6, zcytor5, CRLM3, NR6.1, clf-1.a, wu:fd24a10, zgc:91992
Epitope
Middle Region
(8), (7), (3), (3), (3), (2), (2), (2), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio), Human
(39), (13), (13), (12), (12), (12), (12)
Host
Rabbit
(31), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(30), (10), (10), (4), (3), (2), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN501581
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human CRLF1
Sequence QLSVRWVSPP ALKDFLFQAK YQIRYRVEDS VDWKVVDDVS NQTSCRLAGL
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rat : 100 %, Zebrafish : 100 %
Characteristics This is a rabbit polyclonal antibody against CRLF1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CRLF1
Background CRLF1 belongs to the type I cytokine receptor family. It is cytokine receptor subunit, possibly playing a regulatory role in the immune system and during fetal development. The protein may be involved in nervous system development.Defects in CRLF1 are the cause of cold-induced sweating syndrome 1 and Crisponi syndrome.
Molecular Weight 46 kDa
Gene ID 9244
NCBI Accession NP_004741, NM_004750
UniProt O75462
Research Area Immunology, Innate Immunity, Cytokines
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 422 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Cytokine Receptor-Like Factor 1 (CRLF1) (Middle Region) antibody WB Suggested Anti-CRLF1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Jurkat cell lysate
Background publications Crisponi, Crisponi, Meloni et al.: "Crisponi syndrome is caused by mutations in the CRLF1 gene and is allelic to cold-induced sweating syndrome type 1." in: American journal of human genetics, Vol. 80, Issue 5, pp. 971-81, 2007 (PubMed).

Validation Images
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