RNA (Guanine-9-) Methyltransferase Domain Containing 1 (RG9MTD1) (Middle Region) antibody

Details for Product No. ABIN502036
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Antigen
Synonyms RG9MTD1, rg9mtd1, wu:fb53e06, zgc:103570, HNYA, MRPP1, Rg9mtd1, 1300018J16Rik, D16Ertd454e, Rnmtd1
Epitope
Middle Region
(2), (1), (1), (1)
Reactivity
Human
(7)
Host
Rabbit
(6), (1)
Clonality
Polyclonal
Application
Western Blotting (WB)
(6), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN502036
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Immunogen Synthetic peptide directed towards the middle region of human RG9MTD1
Sequence KKARQIKKEM KAAAREEAKN IKLLETTEED KQKNFLFLRL WDRNMDIAMG
Predicted Reactivity Human : 100 %, Rabbit : 90 %
Characteristics This is a rabbit polyclonal antibody against RG9MTD1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name RG9MTD1
Background RG9MTD1 functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends.
Molecular Weight 47 kDa
Gene ID 54931
NCBI Accession NM_017819, NP_060289
UniProt Q7L0Y3
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 403 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-RNA (Guanine-9-) Methyltransferase Domain Containing 1 (RG9MTD1) (Middle Region) antibody WB Suggested Anti-RG9MTD1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: PANC1 cell lysate
Background publications Scanlan, Gordan, Williamson et al.: "Antigens recognized by autologous antibody in patients with renal-cell carcinoma." in: International journal of cancer. Journal international du cancer, Vol. 83, Issue 4, pp. 456-64, 1999 (PubMed).

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