CAMP-Regulated phosphoprotein, 21kDa (ARPP21) (N-Term) antibody

Details for Product No. ABIN502262
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Antigen
Synonyms Arpp-21, Ppp1r1c, Ppp1r1cl, RGD1307208, RGD1307215, ARPP-21, R3HDM3, RCS, TARPP, 0710001E13Rik, AI853636, D9Bwg1012e, R3hdm3, Tarpp
Epitope
N-Term
(16), (8), (3), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Cow (Bovine), Fruit Fly (Drosophila melanogaster), Human, Chicken
(26), (15), (1)
Host
Rabbit
(28)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(28), (16), (10), (3), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN502262
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Immunogen Synthetic peptide directed towards the N terminal of human ARPP-21
Sequence ESSARPGGES LQDQESIHLQ LSSFSSLQEE DKSRKDDSER EKEKDKNKDK
Predicted Reactivity Western balsam poplar :100 %,   Human :100 %,   Dog :100 %,   Bovine :100 %,   Mouse :100 %,   Rat :100 %,   Chicken :90 %,   Maize :80 %,   Fruit fly :70 %,   Cellular slime mold :70 %,   Grape :70 %,  
Characteristics This is a rabbit polyclonal antibody against ARPP-21. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ARPP-21
Background ARPP-21 contains 1 R3H domain. Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons. Isoform 1 is methylated by CARM1 in immature thymocytes.
Molecular Weight 89 kDa
Gene ID 10777
NCBI Accession NM_016300, NP_057384
UniProt Q9UBL0
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 812 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Brill, Salomon, Ficarro et al.: "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry." in: Analytical chemistry, Vol. 76, Issue 10, pp. 2763-72, 2004 (PubMed).

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