Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 1 (SLC6A1) (Middle Region) antibody

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Antigen
Synonyms A730043E01, GABATHG, GABATR, GAT-1, Gabt, Gabt1, Gat1, XT-1, Xtrp1, si:ch211-280e18.1, si:dkey-164m14.1, slc6a1, GAT1
Epitope
Middle Region
(12), (11), (3), (2), (1), (1), (1), (1), (1)
Reactivity
Chicken, Cow (Bovine), Dog (Canine), Fruit Fly (Drosophila melanogaster), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(29), (24), (17)
Host
Rabbit
(38), (1)
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(35), (17), (12), (4), (3), (2), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human SLC6A1
Sequence CCINSCTSMF AGFVIFSIVG FMAHVTKRSI ADVAASGPGL AFLAYPEAVT
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Chicken : 90 %
Characteristics This is a rabbit polyclonal antibody against SLC6A1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SLC6A1 (SLC6A1 Antibody Abstract)
Background SLC6A1 terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. This protein is the target of psychomotor stimulants such as amphetamines or cocaine.
Molecular Weight 67 kDa
Gene ID 6529
NCBI Accession NP_003033, NM_003042
UniProt P30531
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 599 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 1 (SLC6A1) (Middle Region) antibody (ABIN502435) WB Suggested Anti-SLC6A1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Image no. 2 for anti-Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 1 (SLC6A1) (Middle Region) antibody (ABIN502435) anti-Solute Carrier Family 6 (Neurotransmitter Transporter, GABA), Member 1 (SLC6A1) (Middle Region) antibody (Image 2)
Background publications Gotlib, Joormann, Minor et al.: "HPA axis reactivity: a mechanism underlying the associations among 5-HTTLPR, stress, and depression." in: Biological psychiatry, Vol. 63, Issue 9, pp. 847-51, 2008 (PubMed).

Catalog No. ABIN502435
$289.00
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