RB1-Inducible Coiled-Coil 1 (RB1CC1) (C-Term) antibody

Details for Product No. ABIN503160
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Antigen
Synonyms DKFZp459E2330, CC1, FIP200, 2900055E04Rik, 5930404L04Rik, Cc1, LaXp180
Epitope
C-Term
(8), (7), (3), (2), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Human, Chicken
(29), (26), (13), (12), (12), (12), (11)
Host
Rabbit
(36), (3)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(29), (16), (9), (5), (3), (2), (2), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN503160
289.00 $
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Immunogen Synthetic peptide directed towards the C terminal of human RB1CC1
Sequence SGASRRPWVL GKVMEKEYCQ AKKAQNRFKV PLGTKFYRVK AVSWNKKV
Predicted Reactivity Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Mouse : 100 %, Rat : 100 %
Characteristics This is a rabbit polyclonal antibody against RB1CC1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name RB1CC1
Background RB1CC1 is implicated in the regulation of RB1 expression. It functions as a DNA-binding transcription factor. RB1CC1 is a potent regulator of the RB1 pathway and a mediator that plays a crucial role in muscular differentiation. The expression of RB1CC1 is, thus, a prerequisite for myogenic differentiation. RB1CC1 is frequently mutated in breast cancer and shows characteristics of a classical tumor suppressor gene.
Molecular Weight 183 kDa
Gene ID 9821
NCBI Accession NM_001083617, NP_001077086
UniProt Q8TDY2
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1591 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-RB1-Inducible Coiled-Coil 1 (RB1CC1) (C-Term) antibody WB Suggested Anti-RB1CC1 Antibody Titration: 0.2-1 ug/ml
Positive Control: 293T cell lysate
Background publications Hara, Takamura, Kishi et al.: "FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells." in: The Journal of cell biology, Vol. 181, Issue 3, pp. 497-510, 2008 (PubMed).

Validation Images
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