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Trafficking Protein Particle Complex 2 (TRAPPC2) (Middle Region) antibody

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Synonyms MIP2A, SEDL, SEDT, TRAPPC2P1, TRS20, ZNF547L, hYP38334, 1110066L09Rik, 1810064C02Rik, AW496358, MIP-2A, Sedl, RGD1306925
Middle Region
(20), (16), (3), (2), (1), (1), (1), (1), (1)
Chicken, Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Xenopus laevis
(38), (8), (6), (1), (1), (1), (1)
(35), (4)
(2), (2), (2), (2), (2), (2)
Western Blotting (WB)
(36), (21), (1)
Pubmed 1 reference available
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Quantity 50 μg
Shipping to United States ( )
Availability Will be delivered in 2 to 3 Business Days
Immunogen Synthetic peptide directed towards the middle region of human TRAPPC2
Blocking Peptide Blocking peptide for this product available: ABIN985451
Predicted Reactivity Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %, African clawed frog : 70 %
Characteristics This is a rabbit polyclonal antibody against TRAPPC2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name TRAPPC2 (TRAPPC2 Antibody Abstract)
Background TRAPPC2 prevents MBP1-mediated transcriptional repression and antagonizes MBP1-mediated cell death. TRAPPC2 may play a role in vesicular transport from endoplasmic reticulum to Golgi.The protein encoded by this gene is thought to be part of a large multisubunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind MBP1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseuodogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been found for this gene.
Molecular Weight 16 kDa
Gene ID 6399
NCBI Accession NP_055378, NM_014563
UniProt O14582
Research Area Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.

Antigen size: 140 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Trafficking Protein Particle Complex 2 (TRAPPC2) (Middle Region) antibody (ABIN503168) WB Suggested Anti-TRAPPC2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: <...
Background publications Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome. ..." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Catalog No. ABIN503168
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