Propionyl CoA Carboxylase beta Polypeptide (PCCB) (Middle Region) antibody

Details for Product No. ABIN503849
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Antigen
Synonyms 1300012P06Rik, AI314687, R74805
Epitope
Middle Region
(7), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Human
(21), (4), (2)
Host
Rabbit
(20), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(21), (7), (3), (3), (3), (2), (2), (2), (2)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN503849
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human PCCB
Sequence PGFLPGTAQE YGGIIRHGAK LLYAFAEATV PKVTVITRKA YGGAYDVMSS
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rabbit : 100 %, Rat : 100 %, Sheep : 100 %, Zebrafish : 100 %
Characteristics This is a rabbit polyclonal antibody against PCCB. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PCCB
Background PCCB is a subunit of the propionyl-CoA carboxylase (PCC) enzyme, which is involved in the catabolism of propionyl-CoA. PCC is a mitochondrial enzyme that probably acts as a dodecamer of six alpha subunits and six beta subunits. Defects in this gene are a cause of propionic acidemia type II (PA-2).
Molecular Weight 58 kDa
Gene ID 5096
NCBI Accession NM_000532, NP_000523
UniProt P05166
Research Area Signaling, Metabolism, Amino Acids
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 539 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Propionyl CoA Carboxylase beta Polypeptide (PCCB) (Middle Region) antibody WB Suggested Anti-PCCB Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Human brain
Background publications Desviat, Clavero, Perez-Cerdá et al.: "New splicing mutations in propionic acidemia." in: Journal of human genetics, Vol. 51, Issue 11, pp. 992-7, 2006 (PubMed).

Validation Images
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