Host Cell Factor C1 Regulator 1 (XPO1 Dependent) (HCFC1R1) (Middle Region) antibody

Details for Product No. ABIN503861
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Antigen
Synonyms HPIP, Hpip
Epitope
Middle Region
(9), (8), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Human
(11)
Host
Rabbit
(11)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(11), (7), (7), (2)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN503861
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human HCFC1R1
Sequence LRGAVPMSTK RRLEEEQEPL RKQFLSEENM ATHFSQLSLH NDHPYCSPPM
Predicted Reactivity Bovine : 100 %, Dog : 100 %, Goat : 90 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against HCFC1R1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name HCFC1R1
Background HCFC1R1 regulates HCFC1 activity by modulating its subcellular localization. Overexpression of HCFC1R1 leads to accumulation of HCFC1 in the cytoplasm. HCFC1R1-mediated export may provide the pool of cytoplasmic HCFC1 required for import of virion-derived VP16 into the nucleus.
Molecular Weight 15 kDa
Gene ID 54985
NCBI Accession NP_001002018, NM_001002018
UniProt Q9NWW0
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 138 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Host Cell Factor C1 Regulator 1 (XPO1 Dependent) (HCFC1R1) (Middle Region) antibody WB Suggested Anti-HCFC1R1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Spleen
Background publications Mahajan, Little, Vazquez et al.: "Interaction of HCF-1 with a cellular nuclear export factor." in: The Journal of biological chemistry, Vol. 277, Issue 46, pp. 44292-9, 2002 (PubMed).

Validation Images
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