Proenkephalin (PENK) (Middle Region) antibody

Details for Product No. ABIN504046
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Antigen
Synonyms PENK, penk, penkl, zgc:73353, 2410002E02Rik, ENK, ecat4, AI326464, PPA, Penk1, Penk, Enk, Penk-rs, Penk2
Epitope
Middle Region
(14), (7), (2), (2), (2), (1), (1), (1)
Reactivity
Human
(30), (10), (8), (4), (4), (2), (1)
Host
Rabbit
(30), (12), (9)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(24), (24), (15), (15), (7), (6), (6), (6), (4), (1), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN504046
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Immunogen Synthetic peptide directed towards the middle region of human PENK
Sequence DAEEDDSLAN SSDLLKELLE TGDNRERSHH QDGSDNEEEV SKRYGGFMRG
Predicted Reactivity Human : 100 %
Characteristics This is a rabbit polyclonal antibody against PENK. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PENK
Background Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK (114-133) and PENK (237-258) increase glutamate release in the stri
Molecular Weight 31 kDa
Gene ID 5179
NCBI Accession NP_006202, NM_006211
UniProt P01210
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 267 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Proenkephalin (PENK) (Middle Region) antibody WB Suggested Anti-PENK Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:1562500
Positive Control: Jurkat cell lysate
Background publications Nikoshkov, Drakenberg, Wang et al.: "Opioid neuropeptide genotypes in relation to heroin abuse: dopamine tone contributes to reversed mesolimbic proenkephalin expression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 2, pp. 786-91, 2008 (PubMed).

Validation Images
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