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Details for Product No. ABIN567792

RAD21 Homolog (S. Pombe) (RAD21) (C-Term), (AA 544-631) antibody

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Synonyms SCC1, mKIAA0078, CDLS4, HR21, HRAD21, MCD1, NXP1, hHR21, rad21, wu:fb55d02, wu:fb93f04, hr21, mcd1, nxp1, scc1, nxp-1, xrad21
»Alternatives C-Term, AA 544-631
»Alternatives Human, Mouse (Murine), Rat (Rattus)
Clonality (Clone) Monoclonal ()
»Alternatives Un-conjugated
»Alternatives Immunoprecipitation (IP), Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN567792
Quantity 0.1 mg
478.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 6 to 8 Business Days
Immunogen Recombinant C-terminal fragment (544-631 aa) of Scc1 subunit of Human Cohesin (hRad21).
Clone CM110-2C10
Isotype IgG1
Specificity This antibody reacts with Cohesin (120 kDa) on Western blotting.
Purification Protein-A Agarose Chromatography of hybridoma supernatant.
Alternative Name RAD21
Background Cohesin in eukaryotic cells is mediated by a multisubunit protein complex. Cohesin consists of four proteins: Smc1, Smc3, Scc1/Mcd1/hRad21, which is called kleisin and is the target of the protease separase, and Scc3/Irr1. Cohesin holds sister chromatids together until they separate into daughter cells during mitosis and also prevents splitting of chromosomes once bipolar attachments are made.
Alternate names: Double-strand-break repair protein rad21 homolog, HR21, KIAA0078, NXP1, Nuclear matrix protein 1, SCC1 homolog
Gene ID 5885
NCBI Accession NP_006256
UniProt O60216
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.2 containing 50% Glycerol without preservatives.
Preservative Without preservative
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody (in aliquots) at -20°C.
Expiry Date 12 months
Background publications Hoque, Ishikawa: "Human chromatid cohesin component hRad21 is phosphorylated in M phase and associated with metaphase centromeres." in: The Journal of biological chemistry, Vol. 276, Issue 7, pp. 5059-67, 2001 (PubMed).

Alternatives for antigen "RAD21 Homolog (S. Pombe) (RAD21)", type "Antibodies"
Hosts (45), (15)
Reactivities (58), (25), (18), (12), (12), (12), (12), (1)
Applications (49), (21), (10), (9), (8), (4), (2), (1)
Conjugates (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (16), (9), (7), (2), (1)