IL-17 antibody

Catalog No. ABIN604996

Product Details anti-IL-17 Antibody

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Recognizes mouse Interleukin 17, a 32kD disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.

Purification: Purified from ascites.

Immunogen: E. coli-expressed, recombinant mouse IL-17A

Clone: TC11-18H10

Isotype: IgG1

Application Details

Application Notes: Approved: ELISA, Flo, IHC, IHC-P (10 μg/mL), WB

Usage: ELISA: This antibody can be used in a sandwich ELISA with LS-C41752 as a detection antibody.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Borate buffered saline.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C. Avoid freeze-thaw cycles.

Target Details for IL-17

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Alternative Name: IL17 / IL-17 (IL17 Products)

Background: Name/Gene ID: IL17

Synonyms: IL17