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CD70 Molecule (CD70) antibody

Details for Product No. ABIN610194, Supplier: Login to see
Antigen
  • CD27LG
  • Cd27l
  • Tnfsf7
  • CD27L
  • TNFSF7
Reactivity
Human
133
60
6
2
1
Host
Mouse
77
58
45
3
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
21
19
17
4
2
2
2
1
1
1
1
1
Application
Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS), ELISA
94
62
48
43
21
20
17
14
14
12
5
4
4
2
2
2
2
1
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Immunogen Human WM-1 (Waldenstrpm's macroglobulinemia) cell line.
Clone BU69
Isotype IgG1
Specificity CD70 molecule of approximately 30 kd.
Purification Protein A Column
Alternative Name CD70 (CD70 Antibody Abstract)
Background Standard Gene Symbol: CD70, Gene Family: TNF, Synonyms: CD70, CD27LG, Ki-24 antigen, Surface antigen CD70, CD27 ligand, CD27-L, CD70 antigen, CD70 molecule, TNFSF7
Gene ID 970
UniProt P32970
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways
Application Notes ELISA, Flo, Func, ICC, IHC-Fr
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer 50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 0.5 mg/mL Gentamicin sulfate
Preservative Gentamicin sulfate
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at +4°C. DO NOT FREEZE.
Product cited in: Baki, Marambaud, Efthimiopoulos et al.: "Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 5, pp. 2381-6, 2001 (PubMed).

Huan, van Adelsberg: "Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins." in: The Journal of clinical investigation, Vol. 104, Issue 10, pp. 1459-68, 1999 (PubMed).

Background publications Hirano, Kimoto, Shimoyama et al.: "Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization." in: Cell, Vol. 70, Issue 2, pp. 293-301, 1992 (PubMed).