SH3-Binding Domain Kinase 1 (SBK1) (C-Term) antibody

Details for Product No. ABIN610861, Supplier: Log in to see
Antigen
  • sbk1
  • SBK
  • Sbk
  • brain specific kinase 146
  • SH3-binding domain kinase 1
  • SH3-binding kinase 1
  • bsk146
  • SBK1
  • Sbk1
Epitope
C-Term
4
1
Reactivity
Human, Monkey, Mouse (Murine), Rat (Rattus)
5
2
1
1
Host
Rabbit
5
Clonality
Polyclonal
Application
Western Blotting (WB)
5
Options
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Immunogen Synthetic peptide from C-Terminus of mouse Sbk1 (Q8QZX0, NP_663562). Percent identity by BLAST analysis: Human, Gibbon, Marmoset, Mouse, Rat (100%), Galago, Elephant, Pig, Guinea pig (92%), Xenopus (84%).

Type of Immunogen: Synthetic peptide
Specificity Mouse SBK1
Predicted Reactivity Percent identity by BLAST analysis: Human, Rat (100%) Mouse, Pig, Guinea pig (92%).
Purification Immunoaffinity purified
Alternative Name SBK1 (SBK1 Antibody Abstract)
Background Name/Gene ID: SBK1
Subfamily: NFK
Family: Protein Kinase

Synonyms: SBK1, SH3-binding domain kinase 1, SBK, SH3-binding kinase 1
Gene ID 388228
NCBI Accession NP_663562
UniProt Q52WX2
Application Notes Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Distilled water
Concentration Lot specific
Buffer Lyophilized from PBS with 2 % sucrose
Handling Advice Avoid repeat freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Supplier Images
 image for anti-SH3-Binding Domain Kinase 1 (SBK1) (C-Term) antibody (ABIN610861) anti-SH3-Binding Domain Kinase 1 (SBK1) (C-Term) antibody
Background publications Cantley, Neel: "New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 8, pp. 4240-5, 1999 (PubMed).

Kandel, Hay: "The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB." in: Experimental cell research, Vol. 253, Issue 1, pp. 210-29, 1999 (PubMed).

Alessi, Andjelkovic, Caudwell, Cron, Morrice, Cohen, Hemmings: "Mechanism of activation of protein kinase B by insulin and IGF-1." in: The EMBO journal, Vol. 15, Issue 23, pp. 6541-51, 1997 (PubMed).

Product cited in: Datta, Dudek, Tao, Masters, Fu, Gotoh, Greenberg: "Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery." in: Cell, Vol. 91, Issue 2, pp. 231-41, 1997 (PubMed).