Lysosomal-Associated Membrane Protein 2 (LAMP2) antibody

Antigen: Lysosomal-Associated Membrane Protein 2 (LAMP2)

Synonyms: LAMPB, CD107b, LGP110, Mac3, Lamp-2, Lamp-2a, Lamp-2b, Lamp-2c, MGC82091, LAMP2, MGC127297, lamp2, DKFZp459J126

Clonality: Monoclonal (H4B4)

Host: Please enquire

Reactivity: Human

Conjugate: Un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Catalog no.: ABIN638447

Additional Information

Alternative name: CD107b

Gene ID: 3920

Immunogen: Human PBMC

No Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Isotype: IgG1

Clone: H4B4

Specificity: The mouse monoclonal antibody H4B4 recognizes CD107b / LAMP-2, an extensively glycosylated 100-120 kDa widely expressed lysosome-associated protein.HLDA V., WS Code P007

Application Details

Buffer: Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 micrometer filter sterilized.

Preservative (Components): Azide free

Storage: Store at 2-8°C. Do not use after expiration date stamped on vial label. For long-term storage aliquot, store at -20°C. Avoid freeze/thaw cycles.

Restrictions: For Research Use only

Publications

Product: Denzer, van Eijk, Kleijmeer et al.: "Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 3, pp. 1259-65, 2000 (PubMed).

Borgne-Sanchez, Dupont, Langonné et al.: "Targeted Vpr-derived peptides reach mitochondria to induce apoptosis of alphaVbeta3-expressing endothelial cells." in: Cell death and differentiation, Vol. 14, Issue 3, pp. 422-35, 2007 (PubMed).

Palmer, Fernandez, Bisbing et al.: "Restricted replication and lysosomal trafficking of yellow fever 17D vaccine virus in human dendritic cells." in: The Journal of general virology, Vol. 88, Issue Pt 1, pp. 148-56, 2006 (PubMed).

Kannanganat, Ibegbu, Chennareddi et al.: "Multiple-cytokine-producing antiviral CD4 T cells are functionally superior to single-cytokine-producing cells." in: Journal of virology, Vol. 81, Issue 16, pp. 8468-76, 2007 (PubMed).

Guia, Cognet, de Beaucoudrey et al.: "A role for interleukin-12/23 in the maturation of human natural killer and CD56+ T cells in vivo." in: Blood, Vol. 111, Issue 10, pp. 5008-16, 2008 (PubMed).

Apte, Baz, Groves et al.: "Interferon-gamma and interleukin-4 reciprocally regulate CD8 expression in CD8+ T cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 45, pp. 17475-80, 2008 (PubMed).

Thedrez, Harly, Morice et al.: "IL-21-mediated potentiation of antitumor cytolytic and proinflammatory responses of human V gamma 9V delta 2 T cells for adoptive immunotherapy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 6, pp. 3423-31, 2009 (PubMed).

Meade, Wilson, Holmes et al.: "Proteolytic activation of the cytotoxic phenotype during human NK cell development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 2, pp. 803-13, 2009 (PubMed).