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Details for Product No. ABIN650994

Fatty Acid 2-Hydroxylase (FA2H) (AA 121-148), (Center) antibody

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Synonyms FAAH, FAH1, FAXDC1, SCS7, SPG35, Wdr59, RGD1310347, MGC85470, MGC97767, cb1044, zgc:153777
»Alternatives AA 121-148, Center
»Alternatives Human, Mouse (Murine)
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC)
Pubmed 1 reference available
Catalog no. ABIN650994
Quantity 400 µL
291.50 $   Plus shipping costs $45.00
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Immunogen This FA2H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-148 AA from the Central region of human FA2H.
Clone RB23881
Isotype Ig
Specificity This FA2H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127~157 amino acids from the Central region of human FA2H.
Predicted Reactivity Monkey,Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FA2H
Background FA2H is a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups.
Synonyms: Fatty acid alpha-hydroxylase, Fatty acid 2-hydroxylase,FAAH, FA2H
Molecular Weight 42791 DA
Gene ID 79152
UniProt Q7L5A8
Research Area Cell Signaling, Cell Structure, Metabolism, Neurology
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Uchida, Hama, Alderson et al.: "Fatty acid 2-hydroxylase, encoded by FA2H, accounts for differentiation-associated increase in 2-OH ceramides during keratinocyte differentiation." in: The Journal of biological chemistry, Vol. 282, Issue 18, pp. 13211-9, 2007 (PubMed).

Alternatives for antigen "Fatty Acid 2-Hydroxylase (FA2H)", type "Antibodies"
Hosts (11), (3)
Reactivities (13), (6), (2)
Applications (14), (4), (3), (1), (1)
Epitopes (2), (1), (1), (1), (1)