Magnesium Transporter 1 (MAGT1) (N-Term), (AA 44-71) antibody

Details for Product No. ABIN651247
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Antigen
Epitope
N-Term, AA 44-71
(10), (7)
Reactivity
Human, Mouse (Murine)
(14), (4), (4), (1)
Host
Rabbit
(14)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(14), (8), (7)
Pubmed 3 references available
Quantity 400 μL
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Catalog No. ABIN651247
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Immunogen This MAGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-71 AA from the N-terminal region of human MAGT1.
Clone RB25786
Isotype Ig
Specificity This MAGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-110 amino acids from the N-terminal region of human MAGT1.
Predicted Reactivity Chicken
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name MAGT1
Background MAGT1 encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29.
Synonyms: Implantation-associated protein, IAP, Magnesium transporter protein 1, MagT1,UNQ628/PRO1244, PSEC0084, IAG2, MAGT1
Molecular Weight 38037 DA
Gene ID 84061
UniProt Q9H0U3
Research Area Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Magnesium Transporter 1 (MAGT1) (N-Term), (AA 44-71) antibody Western blot analysis of MAGT1 Antibody (N-term) (ABIN651247) in mouse NIH-3T3 cell line lysates (35 µg/lane).MAGT1 (arrow) was detected using the purified polyclonal antibody.
anti-Magnesium Transporter 1 (MAGT1) (N-Term), (AA 44-71) antibody (2) MAGT1 Antibody (N-term) (ABIN651247) flow cytometric analysis of U251 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Shibatani, David, McCormack et al.: "Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits." in: Biochemistry, Vol. 44, Issue 16, pp. 5982-92, 2005 (PubMed).

Molinari, Foulquier, Tarpey et al.: "Oligosaccharyltransferase-subunit mutations in nonsyndromic mental retardation." in: American journal of human genetics, Vol. 82, Issue 5, pp. 1150-7, 2008 (PubMed).

Zhou, Clapham: "Mammalian MagT1 and TUSC3 are required for cellular magnesium uptake and vertebrate embryonic development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 37, pp. 15750-5, 2009 (PubMed).

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