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Details for Product No. ABIN651535

Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G) (AA 209-238), (Center) antibody

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Antigen
Synonyms EIF3S4, EIF3-P42, eIF3-p44, eIF3-delta, p44, 44kDa, D0Jmb4, Eif3s4, TU-189B2, eif3s4, zgc:56553, eIF3g-A, eif3s4-A, eIF3g, eIF3-S4, An16g05260, AO090011000648
Epitope
»Alternatives AA 209-238, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
Pubmed 2 references available
Catalog no. ABIN651535
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This EIF3G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-238 AA from the Central region of human EIF3G.
Clone RB26846
Isotype Ig
Specificity This EIF3G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-247 amino acids from the Central region of human EIF3G.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus),Xenopus laevis,Zebrafish
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name EIF3G
Background Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. This subunit can bind 18S rRNA.
Synonyms: eIF3 p42, eIF3 p44, Eukaryotic translation initiation factor 3 RNA-binding subunit, eIF-3 RNA-binding subunit, eIF-3-delta, Eukaryotic translation initiation factor 3 subunit 4, Eukaryotic translation initiation factor 3 subunit G, eIF3g,EIF3S4, EIF3G
Molecular Weight 35611  DA
Gene ID 8666
UniProt NP_003746.2, O75821
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Signaling, Chromatin, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Masutani, Sonenberg, Yokoyama et al.: "Reconstitution reveals the functional core of mammalian eIF3." in: The EMBO journal, Vol. 26, Issue 14, pp. 3373-83, 2007 (PubMed).

Zhou, Sandercock, Fraser et al.: "Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18139-44, 2008 (PubMed).

Alternatives for antigen "Eukaryotic Translation Initiation Factor 3, Subunit G (EIF3G)", type "Antibodies"
Hosts (22), (2)
Reactivities (22), (6), (6), (4), (4), (3), (2), (2), (2)
Applications (24), (9), (6), (6), (3), (3), (2), (2)
Epitopes (3), (3), (2), (2), (2), (2), (2), (1), (1), (1)
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