SC31B (C-Term), (AA 1076-1104) antibody

Details for Product No. ABIN651805
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Antigen
Epitope
C-Term, AA 1076-1104
(1), (1)
Reactivity
Human
(1)
Host
Rabbit
(1)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB), Flow Cytometry (FACS)
(1), (1)
Pubmed 3 references available
Quantity 400 μL
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Catalog No. ABIN651805
291.50 $
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Immunogen This SC31B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1076-1104 AA from the C-terminal region of human SC31B.
Clone RB27130
Isotype Ig
Specificity This SC31B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1083-1112 amino acids from the C-terminal region of human SC31B.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Background This gene encodes a protein of unknown function. The protein has moderate similarity to rat VAP1 protein which is an endosomal membrane-associated protein, containing a putative Ca2+/calmodulin-dependent kinase II phosphorylation site.
Synonyms: Protein transport protein Sec31B,SEC31B,SEC31L2
Molecular Weight 128697 DA
Gene ID 25956
NCBI Accession NP_056305
UniProt Q9NQW1
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-SC31B (C-Term), (AA 1076-1104) antibody SC31B Antibody (C-term) (ABIN651805) western blot analysis in NCI-H460 cell line lysates (15 µg/lane). This demonstrates the SC31B antibody detected the SC31B protein (arrow).
anti-SC31B (C-Term), (AA 1076-1104) antibody (2) SC31B Antibody (C-term) (ABIN651805) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Tang, Zhang, Low et al.: "Mammalian homologues of yeast sec31p. An ubiquitously expressed form is localized to endoplasmic reticulum (ER) exit sites and is essential for ER-Golgi transport." in: The Journal of biological chemistry, Vol. 275, Issue 18, pp. 13597-604, 2000 (PubMed).

Grupe, Li, Rowland et al.: "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease." in: American journal of human genetics, Vol. 78, Issue 1, pp. 78-88, 2005 (PubMed).

Stankewich, Stabach, Morrow: "Human Sec31B: a family of new mammalian orthologues of yeast Sec31p that associate with the COPII coat." in: Journal of cell science, Vol. 119, Issue Pt 5, pp. 958-69, 2006 (PubMed).

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