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Estrogen-Related Receptor alpha (ESRRA) (AA 131-159), (Center) antibody

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Synonyms err1, erra, esrral, erralpha, nr3b1, MGC80854, ESRRA, esrl1, LOC100125507, ERRalpha, Err1, Estrra, Nr3b1, Errra, ERR1, ERRa, ESRL1, NR3B1, ESTRRA
AA 131-159, Center
(15), (9), (6), (5), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
(74), (12), (8), (1), (1)
(65), (11)
Clonality (Clone)
Polyclonal ()
(2), (2), (2), (2), (1), (1), (1)
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(58), (17), (15), (11), (11), (7), (5), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Quantity 400 μL
Shipping to United States ( )
Availability Will be delivered in 2 to 4 Business Days
Immunogen This ESRRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-159 AA from the Central region of human ESRRA.
Clone RB22490
Isotype Ig
Specificity This ESRRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138~167 amino acids from the Center region of human ESRRA.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ESRRA (ESRRA Antibody Abstract)
Background ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes.
Synonyms: Steroid hormone receptor ERR1, Estrogen-related receptor, alpha, ERR-alpha, Estrogen receptor-like 1, Nuclear receptor subfamily 3 group B member 1, NR3B1, ESRL1, ERR1, ESRRA
Molecular Weight 45510 Da
Gene ID 2101
UniProt P11474
Research Area Transcription Factors, Signaling, Neurology
Pathways Nuclear Receptor Transcription Pathway
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Estrogen-Related Receptor alpha (ESRRA) (AA 131-159), (Center) antibody (ABIN652575) Western blot analysis of ESRRA Antibody (Center) (ABIN652575) in A375 cell line lysat...
Immunohistochemistry (IHC) image for anti-Estrogen-Related Receptor alpha (ESRRA) (AA 131-159), (Center) antibody (ABIN652575) Formalin-fixed and paraffin-embedded human kidney carcinoma reacted with ESRRA Antibo...
Flow Cytometry (FACS) image for anti-Estrogen-Related Receptor alpha (ESRRA) (AA 131-159), (Center) antibody (ABIN652575) Flow cytometric analysis of 293 cells using ESRRA Antibody (Center)(bottom histogram)...
Background publications Yang, Shigeta, Shi et al.: "Estrogen-related receptor, hERR1, modulates estrogen receptor-mediated response of human lactoferrin gene promoter." in: The Journal of biological chemistry, Vol. 271, Issue 10, pp. 5795-804, 1996 (PubMed).

Wiley, Kraus, Zuo et al.: "SV40 early-to-late switch involves titration of cellular transcriptional repressors." in: Genes & development, Vol. 7, Issue 11, pp. 2206-19, 1993 (PubMed).

Catalog No. ABIN652575
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