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Details for Product No. ABIN652575

Estrogen-Related Receptor alpha (ESRRA) (AA 131-159), (Center) antibody

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Antigen
Synonyms Errra, ERRalpha, ESTRRA, ERRa, ERR1, ESRL1, NR3B1, Err1, Nr3b1, Estrra, err1, erra, esrral, erralpha, nr3b1, MGC80854, ESRRA, esrl1, LOC100125507
Epitope
»Alternatives AA 131-159, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
Pubmed 2 references available
Catalog no. ABIN652575
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This ESRRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-159 AA from the Central region of human ESRRA.
Clone RB22490
Isotype Ig
Specificity This ESRRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138~167 amino acids from the Center region of human ESRRA.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ESRRA
Background ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes.
Synonyms: Steroid hormone receptor ERR1, Estrogen-related receptor, alpha, ERR-alpha, Estrogen receptor-like 1, Nuclear receptor subfamily 3 group B member 1, NR3B1, ESRL1, ERR1, ESRRA
Molecular Weight 45510 Da
Gene ID 2101
UniProt P11474
Research Area Transcription Factors, Signaling, Neurology
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:50-100,FC : 1:10-50,IF : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Wiley, Kraus, Zuo et al.: "SV40 early-to-late switch involves titration of cellular transcriptional repressors." in: Genes & development, Vol. 7, Issue 11, pp. 2206-19, 1993 (PubMed).

Yang, Shigeta, Shi et al.: "Estrogen-related receptor, hERR1, modulates estrogen receptor-mediated response of human lactoferrin gene promoter." in: The Journal of biological chemistry, Vol. 271, Issue 10, pp. 5795-804, 1996 (PubMed).

Alternatives for antigen "Estrogen-Related Receptor alpha (ESRRA)", type "Antibodies"
Hosts (59), (3)
Reactivities (60), (24), (22), (19), (19), (12)
Applications (41), (16), (14), (10), (8), (7), (6), (3), (3), (3), (1)
Conjugates (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (9), (5), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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