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Estrogen-Related Receptor alpha (ESRRA) (AA 131-159), (Center) antibody

Details for Product No. ABIN652575, Supplier: Login to see
Antigen
  • err1
  • erra
  • esrral
  • erralpha
  • nr3b1
  • MGC80854
  • ESRRA
  • esrl1
  • LOC100125507
  • ERRalpha
  • Err1
  • Estrra
  • Nr3b1
  • Errra
  • ERR1
  • ERRa
  • ESRL1
  • NR3B1
  • ESTRRA
Alternatives
anti-Human Estrogen-Related Receptor alpha antibody for Immunohistochemistry (Paraffin-embedded Sections)
Epitope
AA 131-159, Center
15
9
6
5
4
4
3
3
3
2
1
1
1
1
1
1
1
1
1
Reactivity
Human
74
12
8
1
1
Host
Rabbit
65
11
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
58
17
15
11
11
7
5
2
1
1
1
1
Supplier
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Immunogen This ESRRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-159 AA from the Central region of human ESRRA.
Clone RB22490
Isotype Ig
Specificity This ESRRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138~167 amino acids from the Center region of human ESRRA.
Predicted Reactivity Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ESRRA (ESRRA Antibody Abstract)
Background ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes.
Synonyms: Steroid hormone receptor ERR1, Estrogen-related receptor, alpha, ERR-alpha, Estrogen receptor-like 1, Nuclear receptor subfamily 3 group B member 1, NR3B1, ESRL1, ERR1, ESRRA
Molecular Weight 45510 Da
Gene ID 2101
UniProt P11474
Research Area Transcription Factors, Signaling, Neurology
Pathways Nuclear Receptor Transcription Pathway
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-Estrogen-Related Receptor alpha (ESRRA) (AA 131-159), (Center) antibody (ABIN652575) Western blot analysis of ESRRA Antibody (Center) (ABIN652575) in A375 cell line lysat...
Immunohistochemistry (IHC) image for anti-Estrogen-Related Receptor alpha (ESRRA) (AA 131-159), (Center) antibody (ABIN652575) Formalin-fixed and paraffin-embedded human kidney carcinoma reacted with ESRRA Antibo...
Flow Cytometry (FACS) image for anti-Estrogen-Related Receptor alpha (ESRRA) (AA 131-159), (Center) antibody (ABIN652575) Flow cytometric analysis of 293 cells using ESRRA Antibody (Center)(bottom histogram)...
Background publications Yang, Shigeta, Shi et al.: "Estrogen-related receptor, hERR1, modulates estrogen receptor-mediated response of human lactoferrin gene promoter." in: The Journal of biological chemistry, Vol. 271, Issue 10, pp. 5795-804, 1996 (PubMed).

Wiley, Kraus, Zuo et al.: "SV40 early-to-late switch involves titration of cellular transcriptional repressors." in: Genes & development, Vol. 7, Issue 11, pp. 2206-19, 1993 (PubMed).