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CDC14 Cell Division Cycle 14 Homolog B (S. Cerevisiae) (CDC14B) (AA 188-215), (Center) antibody

Details for Product No. ABIN653024, Supplier: Log in to see
Antigen
  • CDC14B
  • 2810432N10Rik
  • A530086E13Rik
  • AA472821
  • CDC14B3
  • Cdc14B1
  • Cdc14B2
  • hCDC14B
Epitope
AA 188-215, Center
13
6
3
3
2
1
1
1
1
Reactivity
Human
28
13
13
Host
Rabbit
24
4
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
14
11
4
3
3
3
3
Supplier
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Immunogen This CDC14B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-215 AA from the Central region of human CDC14B.
Clone RB16909
Isotype Ig
Specificity This CDC14B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271~301 amino acids from the Center region of human CDC14B.
Predicted Reactivity Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name CDC14B (CDC14B Antibody Abstract)
Background CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Synonyms: CDC14 cell division cycle 14 homolog B, Dual specificity protein phosphatase CDC14B, CDC14B
Molecular Weight 56802 DA
Gene ID 8555
UniProt O60729
Research Area Neurology
Pathways
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-CDC14 Cell Division Cycle 14 Homolog B (S. Cerevisiae) (CDC14B) (AA 188-215), (Center) antibody (ABIN653024) Western blot analysis of CDC14B Antibody (Center) (ABIN653024) in 293 cell line lysat...
Flow Cytometry (FACS) image for anti-CDC14 Cell Division Cycle 14 Homolog B (S. Cerevisiae) (CDC14B) (AA 188-215), (Center) antibody (ABIN653024) CDC14B Antibody (Center) (ABIN653024) flow cytometry analysis of 293 cells (bottom hi...
Background publications Bassermann, Frescas, Guardavaccaro et al.: "The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint." in: Cell, Vol. 134, Issue 2, pp. 256-67, 2008 (PubMed).