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Details for Product No. ABIN653024

CDC14 Cell Division Cycle 14 Homolog B (S. Cerevisiae) (CDC14B) (AA 188-215), (Center) antibody

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Antigen
Synonyms CDC14B3, Cdc14B1, Cdc14B2, hCDC14B, AA472821, 2810432N10Rik, A530086E13Rik, CDC14B
Epitope
»Alternatives AA 188-215, Center
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Flow Cytometry (FACS)
Pubmed 1 reference available
Catalog no. ABIN653024
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This CDC14B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-215 AA from the Central region of human CDC14B.
Clone RB16909
Isotype Ig
Specificity This CDC14B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271~301 amino acids from the Center region of human CDC14B.
Predicted Reactivity Mouse (Murine)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name CDC14B
Background CDC14B is a member of the dual specificity protein tyrosine phosphatase family. This protein is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, which suggests the role in cell cycle control. This protein has been shown to interact with and dephosphorylates tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splice of this gene results in 3 transcript variants encoding distinct isoforms.
Synonyms: CDC14 cell division cycle 14 homolog B, Dual specificity protein phosphatase CDC14B, CDC14B
Molecular Weight 56802 DA
Gene ID 8555
UniProt O60729
Research Area Neurology
Application Notes Recommend dilutions: WB : 1:1000,FC : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Bassermann, Frescas, Guardavaccaro et al.: "The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint." in: Cell, Vol. 134, Issue 2, pp. 256-67, 2008 (PubMed).

Alternatives for antigen "CDC14 Cell Division Cycle 14 Homolog B (S. Cerevisiae) (CDC14B)", type "Antibodies"
Hosts (14), (2), (1)
Reactivities (17), (12), (11)
Applications (9), (6), (3), (2), (2), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (2), (1), (1), (1), (1)
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